DESIGN AND FABRICATION MICROFLUIDIC PLATFORM INTEGRATED WITH ELECTROCHEMICAL SENSOR USING 3D PRINTING METHOD

• Main Author: Laeli Munifah, Kurniati
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/74794
• Institution: Institut Teknologi Bandung

Lab-on-chip is the miniaturization of a laboratory into a small integrated chip that is centimeters or millimeters in size. The development of lab-on-chip cannot be separated from the microfluidic platform. Microfluidics is the study of fluid flow in microchannels. Microfluidic platforms allow the movement of small amounts of samples into each of the lab-on-chip functions so that they can be integrated with each other. One type of microfluidic development is an electrochemical testing platform. The microfluidic platform can be integrated with a sensor that can detect certain analytes. The platform is fabricated with materials that do not affect the sensor’s performance. The commonly used microfluidic platform fabrication methods are less integrated, expensive, and require a long process. By using 3D printing, the fabrication process can be more integrated. The fabrication process becomes faster and cheaper. The microfluidic platform that will be integrated with a sensor and potentiostat device must be fabricated properly. The microfluidic platform must be transparent to facilitate sample observation. The microfluidic platform also does not interfere with the performance of the integrated sensor so it can be used as an electrochemical testing platform. Through several design developments, the microfluidic platform integrated with the SPCE sensor and EmStat 4M potentiostat device was successfully fabricated. The fabricated microfluidic platform is transparent. The development of several types of designs resulted in the microfluidic platform repairing the leakage that occurred in previous studies. The platform has a microchannel of ~1000 ?m with fabrication errors almost entirely <10%. The performance of the fabricated microfluidic platform as an electrochemical testing platform has good accuracy and repeatability compared to the droplet method. Tests using the platform also tend to have increased anodic peak current values due to the platform design that allows the sample to hit the SPCE electrode evenly.