DISSOLUTION RATE ENHANCEMENT OF ATORVASTATIN CA BY ADSORPTION ON MESOPOROUS MATERIAL (SBA-15) SYNTHESIZED AT ROOM TEMPERATURE WITH CHLORIDE SALT ADDITION
Background. Atorvastatin Ca belongs to Biopharmaceuticals Classification System (BCS) class Il which has low solubility in water, approximately 0.02 mg/mL. Mesoporous Silica (SBA-15) has high surface area so it would be able to be employed as adsorbent for the enhancement of dissolution by increasin...
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| Format: | Theses |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/78614 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |