ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR TESTING DISSOLUTION OF DIGOXIN TABLET USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
Digoxin is commonly used to treat heart failure. Digoxin is drug with a narrow therapeutic window. According to the Indonesian Pharmacopoeia IV, digoxin tablets dissolution was tested in 0.1 N HCI medium using fluorometric method. In this dissolution medium, digoxin could be hydrolyzed into compound...
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Format: | Theses |
Language: | Indonesia |
Online Access: | https://digilib.itb.ac.id/gdl/view/78772 |
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Institution: | Institut Teknologi Bandung |
Language: | Indonesia |