ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR TESTING DISSOLUTION OF DIGOXIN TABLET USING HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

Digoxin is commonly used to treat heart failure. Digoxin is drug with a narrow therapeutic window. According to the Indonesian Pharmacopoeia IV, digoxin tablets dissolution was tested in 0.1 N HCI medium using fluorometric method. In this dissolution medium, digoxin could be hydrolyzed into compound...

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Bibliographic Details
Main Author: Maryati, Leni
Format: Theses
Language:Indonesia
Online Access:https://digilib.itb.ac.id/gdl/view/78772
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Institution: Institut Teknologi Bandung
Language: Indonesia