SURFACE RESPONSE METHOD FOR SEPARATION OPTIMIZATION OF ERITROMYCIN AND KANAMYCIN USING HPLC WITH FMOC-CL DERIVATIZATION

Background and aims: Erythromycin is a macrolide antibiotic and kanamycin is aminoglycoside antibiotic. Due to the lack of chromophoric groups, analysis of erythromycin and kanamycin preceded by derivatization using FMOC-CI. FMOCCl has reactivity to hydroxyl group on erythromycin and reactivity to a...

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Bibliographic Details
Main Author: Juliawati, Lia
Format: Theses
Language:Indonesia
Online Access:https://digilib.itb.ac.id/gdl/view/79020
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Institution: Institut Teknologi Bandung
Language: Indonesia