DESIGN OF MULTICHANNEL POTENTIOSTAT CIRCUITS AS ELECTROCHEMICAL MEASURING DEVICE FOR TROPONIN I BIOMARKER DETECTION

• Main Author: Marqoh Sirfefa, Nurhayati
• Format: Final Project
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/80514
• Institution: Institut Teknologi Bandung

Electrochemical methods are often used to perform analysis on various biochemical reactions. The problem raised in this final project is the need for an electrochemical measuring instrument for the detection of Troponin I biomarkers. One of the tools for carrying out electrochemical measurements is a potentiostat. To design a complete potentiostat system, a potentiostat analog circuit is needed. This analog circuit will be connected directly to the electrodes or in this case a screen-printed carbon electrode (SPCE) will be used. The analog potentiostat circuit itself includes a buffer circuit, summing amplifier, tranimpedance amplifier and voltage regulator. The implementation of the potentiostat analog circuit itself starts from making a schematic and selecting components. Then, the potentiostat analog circuit will be simulated on LTSpice before later being prototyped on the breadboard. Prototypes for a series of potentiostats were made in stages from one channel to multi-channels. After the trial process, then the analog potentiostat circuit will be combined on the dot matrix PCB with other control unit components, so that it becomes a complete potentiostat circuit.