EFFORT TO IMPROVE MICROMERITIC, MECHANICAL, AND DISSOLUTION BEHAVIOR OF RAMIPRIL THROUGH SPHERICAL COCRYSTALLIZATION TECHNIQUE
Ramipril, a medication prescribed for hypertension and cardiac insufficiency, functions by inhibiting the angiotensin-converting enzyme (ACE). Due to its restricted dissolution in the gastrointestinal tract and inadequate bioavailability (28–35%), its solubility in water is limited to 3.5 µg/m...
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| Format: | Dissertations |
| Language: | Indonesia |
| Online Access: | https://digilib.itb.ac.id/gdl/view/81195 |
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| Institution: | Institut Teknologi Bandung |
| Language: | Indonesia |