COCRYSTAL FORMULATION OF NICOTINAMIDE AND NAPROXEN AND ITS IMPACT ON SOLUBILITY, DISSOLUTION, AND MECHANICAL PROPERTIES

• المؤلف الرئيسي: Mahardika Sherlin, Adinda
• التنسيق: Final Project
• اللغة: Indonesia
• الوصول للمادة أونلاين: https://digilib.itb.ac.id/gdl/view/82314
• المؤسسة: Institut Teknologi Bandung

Naproxen (NPX) is an anti-inflammatory drug belonging to BCS class II with oral bioavalability that is dependent on its solubility. NPX shows poor solubility, dissolution, and compressibilty profile. The purpose of this study is to assess how nicotinamide (NCT) and NPX cocrystal formation affects...