SINTESA FENTOAT

• Main Author: Sumartini, Sri
• Format: Theses
• Language: Indonesia
• Online Access: https://digilib.itb.ac.id/gdl/view/839
• Institution: Institut Teknologi Bandung

Phentoate with trade name ELSAN is one of the organophosphorus pesticides with a low toxicity. It is widely used in Indonesia and being imported for a long time. <br /> Generally the preparation of phentoate are based on two methods. The first method is reaction of alkali metal salts of 0,0-dimethylditiophosphoric acid with an a bromphenylacetic acid and then esterifying with an appropriate alcohol in azeotropic mixtures with carbon tetrachlorida and paratoluensulphonic acid added such as catalyst. The second method is reaction of alkali metal salts of 0,0 dimethylditiophosphoric acid with ethyl a- bromophenylacetic acid. In this study, a bromophenylacetic acid was prepared by brominating phenylacetic acid in the presence or absence of benzen and phosphortrichlorida added such as catalyst 0,0-dimethylditiophosphoric acid was prepared by three methods and then its thin layer chromatogram was compared to each other in the aim to find out which one has high yield with low impurities. Phentoate in this work was prepared by two methods too. The first method was reaction of sodium salt of 0,0- dimethylditiophosphoric acid with an a- bromophenylacetic acid and then esterifying with alcohol in the azeotropic mixtures with benzen and sulphuric acid was added such as catalyst. The second method was reaction of natrium salt of the same 0,0-dimethylditiophosphoric acid with ethyl a-bromophenylacetat. After complete analysis by thin layer chromatography, the total yield of phentoate prepared by the first method was 60% higher then the second and also the impurities of the first method was twice better than the second.