DEVELOPMENT OF CRISPR-CAS9 DELIVERY SYSTEM BASED ON LIPID NANOPARTICLES TARGETED TO TGF-?1 GENE AND ACTIVITY TEST IN VITRO
Diabetic nephropathy (DN) is a microvascular disease triggered by hyperglycemic conditions that can lead to end-stage renal disease. A major obstacle in the conventional treatment of DN is the low effectiveness of drugs, as current therapies focus primarily on symptomatic relief rather than addre...
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Format: | Dissertations |
Language: | Indonesia |
Online Access: | https://digilib.itb.ac.id/gdl/view/86154 |
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Institution: | Institut Teknologi Bandung |
Language: | Indonesia |