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ABSTRACT: <br /> <br /> <br /> The formulation development of rifampicin suspension containing 100 mg/5 ml, using rifampicin crystalline powder of particle size range of 5-20 um had been carried out. The best suspending agent used were 0.15 % of agar and 0.3% of xanthan gum. Physi...
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id-itb.:95772017-09-27T15:32:13Z#TITLE_ALTERNATIVE# Uun Hidayat, Wahyudi Indonesia Theses INSTITUT TEKNOLOGI BANDUNG https://digilib.itb.ac.id/gdl/view/9577 ABSTRACT: <br /> <br /> <br /> The formulation development of rifampicin suspension containing 100 mg/5 ml, using rifampicin crystalline powder of particle size range of 5-20 um had been carried out. The best suspending agent used were 0.15 % of agar and 0.3% of xanthan gum. Physical stability evaluation showed that suspension containing 0.3% of xanthan gum was better compared to that containing 0.15% of agar. Comparative study to marketed product showed a bioavailability of 84.0 % for the xanthan gum suspension and 88.36% for agar suspension. text |
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ABSTRACT: <br />
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The formulation development of rifampicin suspension containing 100 mg/5 ml, using rifampicin crystalline powder of particle size range of 5-20 um had been carried out. The best suspending agent used were 0.15 % of agar and 0.3% of xanthan gum. Physical stability evaluation showed that suspension containing 0.3% of xanthan gum was better compared to that containing 0.15% of agar. Comparative study to marketed product showed a bioavailability of 84.0 % for the xanthan gum suspension and 88.36% for agar suspension. |
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Uun Hidayat, Wahyudi |
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