Perubahan Ekspresi Aquaporin3 Dan Aquaporin4 Setelah Konstipasi Akut Yang Diinduksi Morfin Dan Pemberian Bisakodil Pada Kolon Mencit
Morphine is opioid that prescribed to treat aches and pains. However, morphine often causes Opioid Induce Constipation (OIC) (Hooten et al., 2015). It causes constipation by increasing the expression of AQP3 in the intestine. The increase is occurred indirectly through serotonin so water on the lumi...
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