The Relation Between IGF-1 Levels and Fasting Blood Glucose in Obese Women

• Main Authors: Zakaria Sendy Wardana, Gadis Meinar Sari, Damayanti Tinduh
• Format: Article PeerReviewed
• Language: English; English; English
• Published: Institut Ilmu Kesehatan STRADA Indonesia 2020
• Subjects: R Medicine (General); RA Public aspects of medicine
• Online Access: http://repository.unair.ac.id/102555/1/The%20Relation%20Between%20IGF-1%20Levels%20and%20Fasting%20Blood%20Glucose%20on%20Obese%20Women.pdf; http://repository.unair.ac.id/102555/2/The%20Relation%20Between.pdf; http://repository.unair.ac.id/102555/3/The%20Relation%20Between%20IGF-1%20Levels%20and%20Fasting%20Blood%20Glucose%20on%20Obese%20Women.pdf; http://repository.unair.ac.id/102555/; https://sjik.org/index.php/sjik/article/view/276; https://doi.org/10.30994/sjik.v9i1.276
• Institution: Universitas Airlangga

This study used a cross sectional study method using 39 obese women aged 19-22 years old, Body Mass Index (BMI) 25-35 kg/m2 and Percentage Body Fat (PBF) above 30%, normal blood pressure, heart rate normal rest and normal Hemoglobin (Hb). IGF-1 levels were measured using the Enzym Link Immunosorbent Assay (ELISA) method, while the FBG measurements used ACCU-CHEK® Performance. Data analysis techniques used the Pearson Correlation test with the Statistical Package for Social Science (SPSS). The results obtained an average level of IGF-1 (11,530 ± 4,397) ng/ml and an average FBG (90,153 ± 6,659) mg/dl (r = 0.379) and (p = 0.017). Based on the results of the study, it’s concluded that there is a positive correlation of IGF-1 levels with FBG in obese women. Further research is needed to explain the physiological mechanism of the relation between IGF-1 and FBG in more detail.