Ethyl acetate fraction of Calotropis gigantea roots induce apoptosis through increased G2/M and increased expression of caspase-8 in colon cancer WiDr cell line

• Main Authors: Roihatul Mutiah, -, Aty Widyawaruyanti, -, Sukardiman, -
• Format: Article PeerReviewed
• Language: English; English; English
• Published: MediPoeia 2017
• Subjects: R Medicine; RS Pharmacy and materia medica; RS1-441 Pharmacy and materia medica; RS200-201 Pharmaceutical dosage forms
• Online Access: https://repository.unair.ac.id/102726/1/C24-ARTIKEL.pdf; https://repository.unair.ac.id/102726/2/C24-PREE%20REVIEW.pdf; https://repository.unair.ac.id/102726/3/C24-SIMILARITY.pdf; https://repository.unair.ac.id/102726/; https://www.japsonline.com/abstract.php?article_id=2346&sts=2
• Institution: Universitas Airlangga

Cell apoptosis is one of important mechanisms and used as target for anticancer drugs. This study aimed at determining the mechanism of apoptosis induced by the most active fraction of Calotropis gigantea root extract in colon cancer cells WiDr. Calotropis gigantea root extract (CGRE) was fractionat...