Uji Aktivitas Antibakteri Ekstrak Methanol Kulit Buah Naga Merah (Hylocereus Polyrhizus) Terhadap Methicillin-Susceptible Staphylococcus aureus (MSSA) ATCC 25923 DAN Methicillin-Resistant Staphylococcus aureus (MRSA)

• Main Author: Shazia Hafazhah Aulia
• Format: Theses and Dissertations NonPeerReviewed
• Language: Indonesian; English; Indonesian; Indonesian; Indonesian; Indonesian; Indonesian; Indonesian; Indonesian; Indonesian; Indonesian; Indonesian; Indonesian; Indonesian
• Published: 2020
• Subjects: RA1190-1270 Toxicology. Poisons; RB37-56.5 Clinical pathology. Laboratory technique
• Online Access: http://repository.unair.ac.id/103795/4/1.%20COVER.pdf; http://repository.unair.ac.id/103795/1/2.%20ABSTRACT.pdf; http://repository.unair.ac.id/103795/2/3.%20DAFTAR%20ISI.pdf; http://repository.unair.ac.id/103795/3/4.%20BAB%201%20PENDAHULUAN.pdf; http://repository.unair.ac.id/103795/9/5.%20BAB%202%20TINJAUAN%20PUSTAKA.pdf; http://repository.unair.ac.id/103795/6/6.%20BAB%203%20KERANGKA%20KONSEPTUAL%20DAN%20HIPOTESIS%20PENELITIAN.pdf; http://repository.unair.ac.id/103795/5/7.%20BAB%204%20METODE%20PENELITIAN.pdf; http://repository.unair.ac.id/103795/7/8.%20BAB%205%20HASIL%20DAN%20ANALISIS%20PENELITIAN.pdf; http://repository.unair.ac.id/103795/8/9.%20BAB%206%20PEMBAHASAN.pdf; http://repository.unair.ac.id/103795/9/10.%20BAB%207%20PENUTUP.pdf; http://repository.unair.ac.id/103795/10/11.%20DAFTAR%20PUSTAKA.pdf; http://repository.unair.ac.id/103795/12/12.%20LAMPIRAN.pdf; http://repository.unair.ac.id/103795/11/EMBARGO%20PUBLIKASI%20KARYA%20ILMIAH%20-%20Shazia%20Hafazhah%20Aulia.pdf; http://repository.unair.ac.id/103795/13/SURAT%20PERNYATAAN%20KESEDIAAN%20PUBLIKASI%20ILMIAH%20-%20Shazia%20Hafazhah%20Aulia.pdf; http://repository.unair.ac.id/103795/; http://lib.unair.ac.id
• Institution: Universitas Airlangga

Background : Hylocereus polyrhizus, better known as red dragon fruit, is known to have high antioxidant content dan widely used as a food coloring. However, the utilization of red dragon fruit peel is still narrow. Whereas it has been publicized that red dragon fruit peels have wide antibacterial activity against both gram-negative dan positive, including Staphylococcus aureus. Objective : The purpose of this study was to determine the antibacterial activity of red dragon fruit peel against MSSA (Methicillin-Susceptible Staphylococcus aureus) dan MRSA (Methicillin-Resistant Staphylococcus aureus) Method : This research is an experimental laboratory study using a well-diffusion method to determine the antibacterial activity of red dragon fruit peels against MSSA ATCC 25923 dan MRSA in vitro. Through well-diffusion, we knew the average diameter of the inhibitory zone produced by the extract. In this study, well-diffusion was carried out on 5 concentrations of methanol extract of dragon fruit peels, namely 100%, 75%, 50%, 25% dan 0% (as a negative control), where the 100% concentration contained 1gr / ml extract. DMSO 10% used as a solvent, dan erythromycin 30 μgram dan vancomycin 15 μgram used as a positive control of MSSA dan MRSA,respectively.Result : Based on this research, it is known that the methanol extract of red dragon fruit peels has antibacterial activity against both MSSA dan MRSA. Moreover, it shows a higher antibacterial activity against MRSA. The average diameter of the inhibition zone produced is 0 - 16.54 mm for MSSA dan 12.53-17.32 mm for MRSA. Therefore, red dragon fruit skin has the potential to be developed as an antibiotic against Staphylococcus aureus