Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks : Literature Review
Cervical cancer is a cancer commonly found in women and the treated by chemotherapy. The development of a local vaginal delivery system has the advantage of direct delivery to the target site thereby enabling lower dosing frequencies, increase in bioavailability and minimal systemic effects and may...
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id-langga.1041822021-02-19T10:26:06Z http://repository.unair.ac.id/104182/ Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks : Literature Review Rizqa Ramadhani Trisfalia, - RC0254 Neoplasms. Tumors. Oncology (including Cancer) RM Therapeutics. Pharmacology Cervical cancer is a cancer commonly found in women and the treated by chemotherapy. The development of a local vaginal delivery system has the advantage of direct delivery to the target site thereby enabling lower dosing frequencies, increase in bioavailability and minimal systemic effects and may increase the effectiveness drug. Vaginal environment which is acidic pH and cervical mucus were trapping particles through adhesive interactions. The vaginal drug delivery is developed to be a mucoadhesive system to increase residence time in the vagina. The potential use of vaginal suppositories as an intravaginal mucoadhesive preparation is quite effective because it is easy to use. The efficacy of vaginal mucoadhesive drug delivery systems is affected by characterisctics such as bioadhesive properties, in vitro and in vivo studies. Although, local vaginal delivery system has shown good bioadhesive properties and prolong release, more research needs to find the vaginal suppository formulation to increase the effectiveness of cervical cancer 2020 Thesis NonPeerReviewed text id http://repository.unair.ac.id/104182/1/1.%20HALAMAN%20JUDUL.pdf text en http://repository.unair.ac.id/104182/2/2.%20ABSTRACT%20.pdf text id http://repository.unair.ac.id/104182/3/3.%20DAFTAR%20ISI.pdf text id http://repository.unair.ac.id/104182/4/4.%20BAB%20I%20PENDAHULUAN%20.pdf text id http://repository.unair.ac.id/104182/5/5.%20BAB%20II%20TINJAUAN%20PUSTAKA.pdf text id http://repository.unair.ac.id/104182/6/6.%20BAB%20III%20KERANGKA%20KONSEPTUAL.pdf text id http://repository.unair.ac.id/104182/7/7.%20BAB%20IV%20METODE%20PENELITIAN.pdf text id http://repository.unair.ac.id/104182/8/8.%20BAB%20V%20HASIL%20DAN%20PEMBAHASAN.pdf text id http://repository.unair.ac.id/104182/10/9.%20BAB%20VI%20KESIMPULAN%20DAN%20SARAN.pdf text id http://repository.unair.ac.id/104182/11/10.%20DAFTAR%20PUSTAKA.pdf text id http://repository.unair.ac.id/104182/12/PERMOHONAN%20EMBARGO.pdf Rizqa Ramadhani Trisfalia, - (2020) Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks : Literature Review. Skripsi thesis, UNIVERSITAS AIRLANGGA. http://www.lib.unair.ac.id |
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Universitas Airlangga |
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Universitas Airlangga Library |
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Asia |
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Indonesia Indonesia |
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Universitas Airlangga Library |
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UNAIR Repository |
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Indonesian English Indonesian Indonesian Indonesian Indonesian Indonesian Indonesian Indonesian Indonesian Indonesian |
topic |
RC0254 Neoplasms. Tumors. Oncology (including Cancer) RM Therapeutics. Pharmacology |
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RC0254 Neoplasms. Tumors. Oncology (including Cancer) RM Therapeutics. Pharmacology Rizqa Ramadhani Trisfalia, - Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks : Literature Review |
description |
Cervical cancer is a cancer commonly found in women and the treated by chemotherapy. The development of a local vaginal delivery system has the advantage of direct delivery to the target site thereby enabling lower dosing frequencies, increase in bioavailability and minimal systemic effects and may increase the effectiveness drug. Vaginal environment which is acidic pH and cervical mucus were trapping particles through adhesive interactions. The vaginal drug delivery is developed to be a mucoadhesive system to increase residence time in the vagina. The potential use of vaginal suppositories as an intravaginal mucoadhesive preparation is quite effective because it is easy to use. The efficacy of vaginal mucoadhesive drug delivery systems is affected by characterisctics such as bioadhesive properties, in vitro and in vivo studies. Although, local vaginal delivery system has shown good bioadhesive properties and prolong release, more research needs to find the vaginal suppository formulation to increase the effectiveness of cervical cancer |
format |
Theses and Dissertations NonPeerReviewed |
author |
Rizqa Ramadhani Trisfalia, - |
author_facet |
Rizqa Ramadhani Trisfalia, - |
author_sort |
Rizqa Ramadhani Trisfalia, - |
title |
Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks : Literature Review |
title_short |
Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks : Literature Review |
title_full |
Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks : Literature Review |
title_fullStr |
Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks : Literature Review |
title_full_unstemmed |
Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks : Literature Review |
title_sort |
sistem penghantaran obat mukoadhesif intravaginal sebagai terapi antikanker serviks : literature review |
publishDate |
2020 |
url |
http://repository.unair.ac.id/104182/1/1.%20HALAMAN%20JUDUL.pdf http://repository.unair.ac.id/104182/2/2.%20ABSTRACT%20.pdf http://repository.unair.ac.id/104182/3/3.%20DAFTAR%20ISI.pdf http://repository.unair.ac.id/104182/4/4.%20BAB%20I%20PENDAHULUAN%20.pdf http://repository.unair.ac.id/104182/5/5.%20BAB%20II%20TINJAUAN%20PUSTAKA.pdf http://repository.unair.ac.id/104182/6/6.%20BAB%20III%20KERANGKA%20KONSEPTUAL.pdf http://repository.unair.ac.id/104182/7/7.%20BAB%20IV%20METODE%20PENELITIAN.pdf http://repository.unair.ac.id/104182/8/8.%20BAB%20V%20HASIL%20DAN%20PEMBAHASAN.pdf http://repository.unair.ac.id/104182/10/9.%20BAB%20VI%20KESIMPULAN%20DAN%20SARAN.pdf http://repository.unair.ac.id/104182/11/10.%20DAFTAR%20PUSTAKA.pdf http://repository.unair.ac.id/104182/12/PERMOHONAN%20EMBARGO.pdf http://repository.unair.ac.id/104182/ http://www.lib.unair.ac.id |
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1693176957426991104 |