Effect of Kebar Grass (Biophytum petersianum) Extract on the Seminiferous Tubules in Male Mice (Mus musculus) Treated With 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)

The aim of this research was to analyze the effect of kebar grass on the seminiferous tubules diameter and epithelium thickness of mice exposed to 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD). Twenty five BALB/C mice were used with five treatments (4 mice each group): Negative Control (C-), Positive C...

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Main Authors: Aldis Ingrid Rusyawardani, Widjiati, Suzanita Utama, Chairul Anwar, Lilik Maslachah, Epy Muhammad Luqman
Format: Article PeerReviewed
Language:English
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Published: Nexus Academic Publishers 2020
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Online Access:http://repository.unair.ac.id/104348/4/Bukti%20C03_Effect%20of%20Kebar%20Grass%20%28Biophytum%20petersianum%29%20Extract%20on%20the%20Seminiferous%20Tubules%20in%20Male%20Mice%20%28Mus%20musculus%29%20Treated%20With%202%2C%203%2C%207%2C%208-tetrachlorodibenzo-p-dioxin%20%28TCDD%29.%20%28Penulis%20ke-5%29.pdf
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spelling id-langga.1043482021-03-02T23:11:24Z http://repository.unair.ac.id/104348/ Effect of Kebar Grass (Biophytum petersianum) Extract on the Seminiferous Tubules in Male Mice (Mus musculus) Treated With 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) Aldis Ingrid Rusyawardani Widjiati Suzanita Utama Chairul Anwar Lilik Maslachah Epy Muhammad Luqman SF405.5-407 Laboratory animals SF811-909 Veterinary medicine of special organs, regions, and systems The aim of this research was to analyze the effect of kebar grass on the seminiferous tubules diameter and epithelium thickness of mice exposed to 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD). Twenty five BALB/C mice were used with five treatments (4 mice each group): Negative Control (C-), Positive Control (C+) with TCDD 7μg/kgBW IP, and treatment groups that treated with TCDD 7μg/kgBW IP and Kebar Grass orally for 53 days were presented T1 0,045mg/gBW/day, T2 0,080mg/gBW/day, and T3 0,135mg/gBW/day. Results showed that TCDD decreased the diameter and epithelium thickness of seminiferous tubules, while kebar grass extract was proven to maintain diameters but could not maintain epithelium thickness of of the seminiferous tubules Keywords : Kebar grass, Seminiferous tubule, Tetrachlorodibenzo-p-dioxin (TCDD), Mice Nexus Academic Publishers 2020-05 Article PeerReviewed text en http://repository.unair.ac.id/104348/4/Bukti%20C03_Effect%20of%20Kebar%20Grass%20%28Biophytum%20petersianum%29%20Extract%20on%20the%20Seminiferous%20Tubules%20in%20Male%20Mice%20%28Mus%20musculus%29%20Treated%20With%202%2C%203%2C%207%2C%208-tetrachlorodibenzo-p-dioxin%20%28TCDD%29.%20%28Penulis%20ke-5%29.pdf text en http://repository.unair.ac.id/104348/3/Peer%20review%20C03_Effect%20of%20Kebar%20Grass%20%28Biophytum%20petersianum%29%20Extract%20on%20the%20Seminiferous%20Tubules%20in%20Male%20Mice%20%28Mus%20musculus%29%20Treated%20With%202%2C%203%2C%207%2C%208-tetrachlorodibenzo-p-dioxin%20%28TCDD%29.%20%28Penulis%20ke-5%29.pdf text en http://repository.unair.ac.id/104348/1/C%2003.%20Effect%20of%20Kebar%20Grass%20%28Biophytum%20petersianum%29.pdf Aldis Ingrid Rusyawardani and Widjiati and Suzanita Utama and Chairul Anwar and Lilik Maslachah and Epy Muhammad Luqman (2020) Effect of Kebar Grass (Biophytum petersianum) Extract on the Seminiferous Tubules in Male Mice (Mus musculus) Treated With 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD). Advances In Animal And Veterinary Sciences, 8 (5). pp. 519-523. ISSN 2309-3331, E ISSN 2307-8316
institution Universitas Airlangga
building Universitas Airlangga Library
continent Asia
country Indonesia
Indonesia
content_provider Universitas Airlangga Library
collection UNAIR Repository
language English
English
English
topic SF405.5-407 Laboratory animals
SF811-909 Veterinary medicine of special organs, regions, and systems
spellingShingle SF405.5-407 Laboratory animals
SF811-909 Veterinary medicine of special organs, regions, and systems
Aldis Ingrid Rusyawardani
Widjiati
Suzanita Utama
Chairul Anwar
Lilik Maslachah
Epy Muhammad Luqman
Effect of Kebar Grass (Biophytum petersianum) Extract on the Seminiferous Tubules in Male Mice (Mus musculus) Treated With 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)
description The aim of this research was to analyze the effect of kebar grass on the seminiferous tubules diameter and epithelium thickness of mice exposed to 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD). Twenty five BALB/C mice were used with five treatments (4 mice each group): Negative Control (C-), Positive Control (C+) with TCDD 7μg/kgBW IP, and treatment groups that treated with TCDD 7μg/kgBW IP and Kebar Grass orally for 53 days were presented T1 0,045mg/gBW/day, T2 0,080mg/gBW/day, and T3 0,135mg/gBW/day. Results showed that TCDD decreased the diameter and epithelium thickness of seminiferous tubules, while kebar grass extract was proven to maintain diameters but could not maintain epithelium thickness of of the seminiferous tubules Keywords : Kebar grass, Seminiferous tubule, Tetrachlorodibenzo-p-dioxin (TCDD), Mice
format Article
PeerReviewed
author Aldis Ingrid Rusyawardani
Widjiati
Suzanita Utama
Chairul Anwar
Lilik Maslachah
Epy Muhammad Luqman
author_facet Aldis Ingrid Rusyawardani
Widjiati
Suzanita Utama
Chairul Anwar
Lilik Maslachah
Epy Muhammad Luqman
author_sort Aldis Ingrid Rusyawardani
title Effect of Kebar Grass (Biophytum petersianum) Extract on the Seminiferous Tubules in Male Mice (Mus musculus) Treated With 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)
title_short Effect of Kebar Grass (Biophytum petersianum) Extract on the Seminiferous Tubules in Male Mice (Mus musculus) Treated With 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)
title_full Effect of Kebar Grass (Biophytum petersianum) Extract on the Seminiferous Tubules in Male Mice (Mus musculus) Treated With 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)
title_fullStr Effect of Kebar Grass (Biophytum petersianum) Extract on the Seminiferous Tubules in Male Mice (Mus musculus) Treated With 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)
title_full_unstemmed Effect of Kebar Grass (Biophytum petersianum) Extract on the Seminiferous Tubules in Male Mice (Mus musculus) Treated With 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)
title_sort effect of kebar grass (biophytum petersianum) extract on the seminiferous tubules in male mice (mus musculus) treated with 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (tcdd)
publisher Nexus Academic Publishers
publishDate 2020
url http://repository.unair.ac.id/104348/4/Bukti%20C03_Effect%20of%20Kebar%20Grass%20%28Biophytum%20petersianum%29%20Extract%20on%20the%20Seminiferous%20Tubules%20in%20Male%20Mice%20%28Mus%20musculus%29%20Treated%20With%202%2C%203%2C%207%2C%208-tetrachlorodibenzo-p-dioxin%20%28TCDD%29.%20%28Penulis%20ke-5%29.pdf
http://repository.unair.ac.id/104348/3/Peer%20review%20C03_Effect%20of%20Kebar%20Grass%20%28Biophytum%20petersianum%29%20Extract%20on%20the%20Seminiferous%20Tubules%20in%20Male%20Mice%20%28Mus%20musculus%29%20Treated%20With%202%2C%203%2C%207%2C%208-tetrachlorodibenzo-p-dioxin%20%28TCDD%29.%20%28Penulis%20ke-5%29.pdf
http://repository.unair.ac.id/104348/1/C%2003.%20Effect%20of%20Kebar%20Grass%20%28Biophytum%20petersianum%29.pdf
http://repository.unair.ac.id/104348/
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