Analyses of Precore and Core Promoter Mutations of Hepatitis B Virus in Patients with Chronic Hepatitis B in Surabaya, Indonesia

• Main Authors: Juniastuti, Eduardus Bimo Aksono Herupradoto, Takako Utsumi, Yoshihiko Yano, Soetjipto, Yoshitake Hayashi, Hak Hotta, Fedik Abdul Rantam, Hernomo Ontoseno Kusumobroto, Maria Inge Lusida
• Format: Article PeerReviewed
• Language: English; English; English
• Published: Indonesian Society for Microbiology 2010
• Subjects: R Medicine (General); RC Internal medicine
• Online Access: http://repository.unair.ac.id/104447/1/Analyses.pdf; http://repository.unair.ac.id/104447/2/Analyses.pdf; http://repository.unair.ac.id/104447/3/Analyses%20of%20Precore%20and%20Core%20Promoter%20Mutations%20of%20Hepatitis%20B%20Virus%20in%20Patients%20with%20Chronic%20Hepatitis%20B%20in%20Surabaya%2C%20Indonesia.pdf; http://repository.unair.ac.id/104447/; https://www.researchgate.net/publication/277110568_Analyses_of_Precore_and_Core_Promoter_Mutations_of_Hepatitis_B_Virus_in_Patients_with_Chronic_Hepatitis_B_in_Surabaya_Indonesia
• Institution: Universitas Airlangga

Mutations of precore (A1896) and core promoter (T1762/A1764) of hepatitis B virus can reduce HBeAg production. These mutations are frequently found in the late HBeAg seroconversion. However, it has been a controversy about the role played by precore and core promoter mutations in determining outcome...