Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks
Cervical cancer is a cancer commonly found in women and the treated by chemotherapy. The development of a local vaginal delivery system has the advantage of direct delivery to the target site thereby enabling lower dosing frequencies, increase in bioavailability and minimal systemic effects and may...
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id-langga.1048262021-03-14T05:14:41Z http://repository.unair.ac.id/104826/ Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks Rizqa Ramadhani Trisfalia, - RM671-671.5 Nonprescription drugs. Patent medicines RS1-441 Pharmacy and materia medica Cervical cancer is a cancer commonly found in women and the treated by chemotherapy. The development of a local vaginal delivery system has the advantage of direct delivery to the target site thereby enabling lower dosing frequencies, increase in bioavailability and minimal systemic effects and may increase the effectiveness drug. Vaginal environment which is acidic pH and cervical mucus were trapping particles through adhesive interactions. The vaginal drug delivery is developed to be a mucoadhesive system to increase residence time in the vagina. The potential use of vaginal suppositories as an intravaginal mucoadhesive preparation is quite effective because it is easy to use. The efficacy of vaginal mucoadhesive drug delivery systems is affected by characterisctics such as bioadhesive properties, in vitro and in vivo studies. Although, local vaginal delivery system has shown good bioadhesive properties and prolong release, more research needs to find the vaginal suppository formulation to increase the effectiveness of cervical cancer. 2020 Thesis NonPeerReviewed text id http://repository.unair.ac.id/104826/1/1.%20HALAMAN%20JUDUL.pdf text en http://repository.unair.ac.id/104826/2/2.%20ABSTRACT%20.pdf text id http://repository.unair.ac.id/104826/3/3.%20DAFTAR%20ISI.pdf text id http://repository.unair.ac.id/104826/4/4.%20BAB%20I%20PENDAHULUAN%20.pdf text id http://repository.unair.ac.id/104826/5/5.%20BAB%20II%20TINJAUAN%20PUSTAKA.pdf text id http://repository.unair.ac.id/104826/6/6.%20BAB%20III%20KERANGKA%20KONSEPTUAL.pdf text id http://repository.unair.ac.id/104826/7/7.%20BAB%20IV%20METODE%20PENELITIAN.pdf text id http://repository.unair.ac.id/104826/10/8.%20BAB%20V%20HASIL%20DAN%20PEMBAHASAN.pdf text id http://repository.unair.ac.id/104826/8/9.%20BAB%20VI%20KESIMPULAN%20DAN%20SARAN.pdf text id http://repository.unair.ac.id/104826/9/10.%20DAFTAR%20PUSTAKA.pdf text id http://repository.unair.ac.id/104826/11/FF.F.36-21-Rizqa%20Ramadhani%20Trisfalia_051611133188_Embargo.pdf Rizqa Ramadhani Trisfalia, - (2020) Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks. Skripsi thesis, UNIVERSITAS AIRLANGGA. http://lib.unair.ac.id |
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Indonesia Indonesia |
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Universitas Airlangga Library |
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RM671-671.5 Nonprescription drugs. Patent medicines RS1-441 Pharmacy and materia medica |
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RM671-671.5 Nonprescription drugs. Patent medicines RS1-441 Pharmacy and materia medica Rizqa Ramadhani Trisfalia, - Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks |
description |
Cervical cancer is a cancer commonly found in women and the treated by chemotherapy. The development of a local vaginal delivery system has the advantage of direct delivery to the target site thereby enabling lower dosing frequencies, increase in bioavailability and minimal systemic effects and may increase the effectiveness drug. Vaginal environment which is acidic pH and cervical mucus were trapping particles through adhesive interactions. The vaginal drug delivery is developed to be a mucoadhesive system to increase residence time in the vagina. The potential use of vaginal suppositories as an intravaginal mucoadhesive preparation is quite effective because it is easy to use. The efficacy of vaginal mucoadhesive drug delivery systems is affected by characterisctics such as bioadhesive properties, in vitro and in vivo studies. Although, local vaginal delivery system has shown good bioadhesive properties and prolong release, more research needs to find the vaginal suppository formulation to increase the effectiveness of cervical cancer. |
format |
Theses and Dissertations NonPeerReviewed |
author |
Rizqa Ramadhani Trisfalia, - |
author_facet |
Rizqa Ramadhani Trisfalia, - |
author_sort |
Rizqa Ramadhani Trisfalia, - |
title |
Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks |
title_short |
Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks |
title_full |
Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks |
title_fullStr |
Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks |
title_full_unstemmed |
Sistem Penghantaran Obat Mukoadhesif Intravaginal Sebagai Terapi Antikanker Serviks |
title_sort |
sistem penghantaran obat mukoadhesif intravaginal sebagai terapi antikanker serviks |
publishDate |
2020 |
url |
http://repository.unair.ac.id/104826/1/1.%20HALAMAN%20JUDUL.pdf http://repository.unair.ac.id/104826/2/2.%20ABSTRACT%20.pdf http://repository.unair.ac.id/104826/3/3.%20DAFTAR%20ISI.pdf http://repository.unair.ac.id/104826/4/4.%20BAB%20I%20PENDAHULUAN%20.pdf http://repository.unair.ac.id/104826/5/5.%20BAB%20II%20TINJAUAN%20PUSTAKA.pdf http://repository.unair.ac.id/104826/6/6.%20BAB%20III%20KERANGKA%20KONSEPTUAL.pdf http://repository.unair.ac.id/104826/7/7.%20BAB%20IV%20METODE%20PENELITIAN.pdf http://repository.unair.ac.id/104826/10/8.%20BAB%20V%20HASIL%20DAN%20PEMBAHASAN.pdf http://repository.unair.ac.id/104826/8/9.%20BAB%20VI%20KESIMPULAN%20DAN%20SARAN.pdf http://repository.unair.ac.id/104826/9/10.%20DAFTAR%20PUSTAKA.pdf http://repository.unair.ac.id/104826/11/FF.F.36-21-Rizqa%20Ramadhani%20Trisfalia_051611133188_Embargo.pdf http://repository.unair.ac.id/104826/ http://lib.unair.ac.id |
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1694271307230740480 |