Camellia sinensis with its active compound EGCG can decrease necroptosis via inhibition of HO-1 expression

• Main Authors: Abdulloh Machin, Djoko Agus Purwanto, Nasronudin, Paulus Sugianto, Aulanni'am, Imam Subadi, Imam Susilo, Chrismawan Ardianto, Afif Nurul Hidayati, Budi Utomo
• Format: Article PeerReviewed
• Language: English; English; English
• Published: Foundation for Enviromental Protection and Research 2020
• Subjects: R Medicine (General); RC Internal medicine
• Online Access: http://repository.unair.ac.id/105440/1/Camellia%20sinensis%20with%20its%20active%20compound%20EGCG%20can%20decrease%20necroptosis%20via%20inhibition%20of%20HO-1%20expression.pdf; http://repository.unair.ac.id/105440/2/Camellia%20sinensis%20with%20is%20active%20compound%20EGCG%20can%20decrease%20necroptosis%20via%20inhibitionof%20HO-1%20expression.pdf; http://repository.unair.ac.id/105440/3/Camellia%20sinensis%20with%20its%20active%20compound%20EGCG%20can%20decrease%20necroptosis%20via%20inhibition%20of%20HO-1%20expression.pdf; http://repository.unair.ac.id/105440/; http://www.ejobios.org/article/camellia-sinensis-with-its-active-compound-egcg-can-decrease-necroptosis-via-inhibition-of-ho-1-7705
• Institution: Universitas Airlangga

Stroke is the most common neurological disorder in the word. During ischemic stroke there is increasing of oxidative stress. Green tea (Camellia sinensis) have antioxidant and free radical scavenger effect. In vivo study using male Rattus Novergicus with 5 group, control MCAO group, EGCG 10 mg/kgBW,...