Decidual killer immunoglobulin-like receptor (kir)2dl1 expression and the onset of preeclampsia, birth weight and placental weight in early and late onset preeclampsia

• Main Authors: Khairunnisa Abd Rauf, Gustaaf A. Dekker, Agus Sulistyono, Aditiawarman, Ariyanto Harsono, Khanisyah Erza Gumilar, Ernawati, Erry Gumilar Dachlan
• Format: Other NonPeerReviewed
• Language: English; English
• Published: ScenceDirect 2018
• Subjects: R Medicine (General); RG Gynecology and obstetrics
• Online Access: http://repository.unair.ac.id/105911/1/Decidual%20Killer.pdf; http://repository.unair.ac.id/105911/2/Decidual.pdf; http://repository.unair.ac.id/105911/; https://www.sciencedirect.com/science/article/pii/S2210778918303568?via%3Dihub; https://doi.org/10.1016/j.preghy.2018.08.166
• Institution: Universitas Airlangga

Introduction Successful remodelling of spiral artery ensures adequate uteroplacental perfusion and sufficient nutrient supply to the fetus. HLA-C interaction with maternal KIR determines the outcome of spiral artery remodelling. Strong inhibitory KIR2DL1 lower the expression of cytokines and angioge...