Gene p53 Mutations after the Induction of 7,12-Dimethylbenz(a)anthracene (DMBA) and Administration of Anti-Carcinogenesis Properties of Gynura procumbens in Sprague Dawley Rats

• Main Authors: Abdul Gofur, -, Iwan Sahrial Hamid, -, Dwi Listyorini, -
• Format: Article PeerReviewed
• Language: English; English; English
• Published: Universitas Brawijaya 2015
• Subjects: R735-854 Medical education. Medical schools. Research
• Online Access: https://repository.unair.ac.id/107316/1/Gene%20p53%20Mutations%20after%20the%20Induction%20of%207%2C12.pdf; https://repository.unair.ac.id/107316/6/Validasi%20Gene%20p53%20Mutations%20after%20the%20Induction%20of%207%2C12-Dimethylbenz%28a%29anthracene%20%28DMBA%29.pdf; https://repository.unair.ac.id/107316/2/Turnitin.pdf; https://repository.unair.ac.id/107316/
• Institution: Universitas Airlangga

Objective: The aim of this research is to study p53 gene mutations in the mammary gland of DMBA-induced Sprague Dawley rats treated with the ethanol extract of Gynura procumbens. Methods: Sprague Dawley female rats aged 40 days were used. DMBA positive control animals were treated with 20 mg/kg bw...