Disease-free survival and overall survival of cervical cancer patients after radical hysterectomy and pelvic lymph-node dissection

• Main Authors: Brahmana Askandar, -, Primandono Perbowo, -, Ardi Eko Marsanto, -
• Format: Article PeerReviewed
• Language: English; English; English; English
• Published: Foundation for Enviromental Protection and Research 2020
• Subjects: R Medicine (General); RG Gynecology and obstetrics
• Online Access: https://repository.unair.ac.id/107639/1/Disease-free%20survival%20and%20overall%20survoval%20of%20cervical%20cancer%20patients%20after%20redical%20hysterectomy%20and%20pelvic%20lymph-node%20dissection.pdf; https://repository.unair.ac.id/107639/2/Disease-free.pdf; https://repository.unair.ac.id/107639/3/Disease-free%20survival%20and%20overall%20survoval%20of%20cervical%20cancer%20patients%20after%20redical%20hysterectomy%20and%20pelvic%20lymph-node%20dissection.pdf; https://repository.unair.ac.id/107639/6/Bukti%20Etik%20No%203.pdf; https://repository.unair.ac.id/107639/; http://www.ejobios.org/article/disease-free-survival-and-overall-survival-of-cervical-cancer-patients-after-radical-hysterectomy-7700
• Institution: Universitas Airlangga

Introduction: Radical Hysterectomy and Pelvic Lymph-Node Dissection (RH-PLND), with or without Neoadjuvant Chemotherapy (NAC) nor Adjuvant Therapy (AT), is still the treatment of choice in stages IB-IIB of cervical cancer due to limited access to concurrent chemoradiotherapy. This study aimed to find out the 3-year Disease-Free Survival (DFS) and Overall Survival (OS) in post-RH-PLND for cervical cancer patients. Methods: This was a restrospective descriptive observational study. Sample was divided into 4 groups [group 1: RH-PLND and group 2: RH-PLND + AT (operable group); group 3: NAC + RH-PLND + AT and group 4: NAC + RH-PLND (inoperable group)]. Results: Total of eight recurrences and six mortalities, with the highest 3-years DFS and OS in group 2 (91.7%) and 1 (100%), respectively. Group 3 had the lowest 3-years DFS and OS compared to other groups (67.4 and 65.6%, respectively). Most recurrence and mortality occured in the inoperable group (five and four patients). Conclusion: The highest DFS and OS among all groups was post RH-PLND cervical cancer patients who get adjuvant therapy group and post-RH-PLND without parametric infiltration pre-operation and positive prognosis factors group, respectively.