Kinship Analysis on Paternity Test Through Str Codis Locus [CSF1PO, THOI, TPOX & vWA] From Maduranese Siblings in Surabaya

• Main Authors: Ahmad Yudianto, -, Agung Sosiawan, -, Fery Setiawan, -, Reni Sumino, -
• 格式: Article PeerReviewed
• 語言: English; English; English; English
• 出版: Faculty of Medicine and Health Sciences, University Putra Malaysia 2021
• 主題: R Medicine (General); RA1001-1171 Forensic medicine. Medical jurisprudence. Legal medicine
• 在線閱讀: https://repository.unair.ac.id/110857/1/Kinship%20Analysis%20on%20Paternity%20Test%20Through%20Str%20Codis%20Locus%20%5BCSF1PO%2C%20THOI%2C%20TPOX%20%26%20vWA%5D%20From%20Maduranese%20Siblings%20in%20Surabaya.pdf; https://repository.unair.ac.id/110857/2/Bukti%20Korespondensi%20Kinship%20Analysis.pdf; https://repository.unair.ac.id/110857/3/Kinship%20Analysis.pdf; https://repository.unair.ac.id/110857/4/Kinship%20Analysis%20on%20Paternity%20Test%20Through%20Str%20Codis%20Locus%20%5BCSF1PO%2C%20THOI%2C%20TPOX%20%26%20vWA%5D%20From%20Maduranese%20Siblings%20in%20Surabaya.pdf; https://repository.unair.ac.id/110857/; https://medic.upm.edu.my/jurnal_kami/malaysian_journal_of_medicine_and_health_sciences_mjmhs/mjmhs_vol17_supp_2_april_2021-61401
• 機構: Universitas Airlangga

Introduction: Paternity test is a DNA examination to determine whether a man is a biological father of a child through DNA pattern comparison between the child and the suspected father to verify DNA inheritance proof. Methods: This study was conducted through analysis of kinship analysis application on paternity test through STR CODIS examination in siblings using peripheral bloods samples of forty samples Madurese 3 generations. The examined locuses were CSF1PO, TH01, TPOX, vWA. Results: DNA samples isolates found that the mean level of DNA was 595.35 ± 4.15ng/µl, whereas the range of purity was 1.17 – 1.29. From this study, alleles from maduranese family population in Surabaya was variable, the highest percentage was CSF1PO locus allele 9 [33.75%], THO1 allele 8 [26.25%], TPOX allele 9 [32.5%] and vWA allele 17 [21.25%]. This study also revealed shared alleles on one sibling allele, the highest was 2 shared alleles on CSF1PO [70%], THO1 [100%], TPOX [70%] and vWA locus [90%]. Conclusion: THOI locus had 100% 2 shared alleles so that it was recommend using STR locus to identify kinship on Madurese in Surabaya.