Mechanism of Bone Metabolism Interruption Due to High Intensity Physical Exercise

• Main Authors: Gadis Meinar Sari, -, Soetjipto, -, Lilik Herawati, -
• Format: Article PeerReviewed
• Language: English; English; English
• Published: 0975-8453 2020
• Subjects: R Medicine (General); RA Public aspects of medicine
• Online Access: https://repository.unair.ac.id/111664/1/Mechanism%20of%20Bone%20Metabolism%20Interruption%20Due%20to%20High%20Intensity%20Physical%20Exercise.pdf; https://repository.unair.ac.id/111664/3/Mechanism%20of%20Bone%20Metabolism%20Interruption%20Due%20to%20High%20Intensity%20Physical%20Exercise.pdf; https://repository.unair.ac.id/111664/6/Peer%20Review%20Final%20%2006.pdf; https://repository.unair.ac.id/111664/; https://www.sysrevpharm.org/abstract/mechanism-of-bone-metabolism-interruption-due-to-high-intensity-physical-exercise-66631.html
• Institution: Universitas Airlangga

Background: High-intensity physical exercise affects the increase of cortisol secretion which knows as the main glucocorticoid in the body and causes a decrease in osteoprotegerin (OPG) activity. Glucocorticoids also work directly on osteoblasts and osteocytes through glucocorticoid receptors (GRα)...