The Relationship Of Insulin‑Like Growth Factor 1 With Bone Mass In Obese Female

• Main Authors: Adek Ardiansyah, -, Lilik Herawati, -, Damayanti Tinduh, -
• Format: Article PeerReviewed
• Language: English; English; English
• Published: STIKes Surya Mitra Husada Kediri 2020
• Subjects: R Medicine (General); RA Public aspects of medicine
• Online Access: https://repository.unair.ac.id/111713/1/The%20Relationship%20Of%20Insulin%E2%80%91Like%20Growth%20Factor%201%20With%20Bone%20Mass%20In%20Obese%20Female.pdf; https://repository.unair.ac.id/111713/3/The%20Relationship%20Of%20Insulin%E2%80%91Like%20Growth%20Factor%201%20With%20Bone%20Mass%20In%20Obese%20Female.pdf; https://repository.unair.ac.id/111713/6/Peer%20Review%20Final%20%2021.pdf; https://repository.unair.ac.id/111713/; https://sjik.org/index.php/sjik/article/view/423; https://doi.org/10.30994/sjik.v9i2.423
• Institution: Universitas Airlangga

This study aimed to analyze the relationship of insulin-like growth factor 1 with bone mass in obese female. This study used a cross sectional study method using 30 obese women aged 19-23 years, body mass index (BMI) 25-35 kg / m2, normal blood pressure, normal resting heart rate (RHR), normal hemoglobin (Hb). and fasting blood glucose (FBG) <100 mg / dL. Measurement of IGF-1 levels used the Enzym Link Immunosorbent Assay (ELISA) method. Measurement of bone mass using TANITA (Body Composition Analyzer DC3607601 (2) -1604 FA, TANITA Corporation of America, Inc., USA). The data analysis technique used the Pearson product-moment test with Statistical Package for Social Science (SPSS). The results showed that mean levels of IGF-1 (1.17 ± 0.10) ng / mL and bone mass (2.49 ± 0.06) kg (r = 0.712, P ≤ 0.001). Our findings suggest that there was a positive correlation between IGF-1 levels and bone mass.