Physicochemical and Cytotoxicity Characterization of Injectable Bone Substitute Based on Hydroxyapatite - Chitosan - Streptomycin for Spinal Tuberculosis Cases

• Main Authors: Systi Adi Rachmawati, -, Dyah Hikmawati, -, Aniek Setiya Budiatin, -, Alfian Pramudita Putra, -
• Format: Article PeerReviewed
• Language: English; English; English
• Published: Trans Tech Publications 2019
• Subjects: R Medicine; RM Therapeutics. Pharmacology; RS Pharmacy and materia medica
• Online Access: https://repository.unair.ac.id/112877/7/C-07%20Artikel%20dan%20SJR.pdf; https://repository.unair.ac.id/112877/9/C-07_Kualitas_Karil_001.pdf; https://repository.unair.ac.id/112877/3/C-07%20Similarity_001.pdf; https://repository.unair.ac.id/112877/; https://www.scientific.net/MSF.966.133; https://doi.org/10.4028/www.scientific.net/MSF.966.133
• Institution: Universitas Airlangga

Injectable bone substitute (IBS) based on hydroxyapatite, chitosan and streptomycin has been developed succesfully. The IBS was made by mixturing 20% w/v hydroxyapatite and varying the chitosan ratio of 60:40, 65:35, 70:30, 75:25 and adding streptomycin as antibiotic substance. The mixture was added...