Signaling Pathway and Transcriptional Regulation in Osteoblasts during Bone Healing: Direct Involvement of Hydroxyapatite as a Biomaterial

• Main Authors: Junaidi Khotib, -, Maria Apriliani Gani, -, Aniek Setiya Budiatin, -, Maria Lucia Ardhani Dwi Lestari, -, Erreza Rahadiansyah, -, Chrismawan Ardianto, -
• Format: Article PeerReviewed
• Language: English; English; English; English; English; English
• Published: MDPI Multidisciplinary Digital Publishing Institute 2021
• Subjects: R Medicine; RS Pharmacy and materia medica; RS1-441 Pharmacy and materia medica; RS200-201 Pharmaceutical dosage forms
• Online Access: https://repository.unair.ac.id/112897/7/C-04%20Artikel%20dan%20SJR.pdf; https://repository.unair.ac.id/112897/9/C-04_Kualitas_Karil_001.pdf; https://repository.unair.ac.id/112897/3/C-04%20Similarity_001.pdf; https://repository.unair.ac.id/112897/11/Artikel%20C-17.pdf; https://repository.unair.ac.id/112897/12/%28C-17%29%20Kualitas%20Karil.pdf; https://repository.unair.ac.id/112897/13/Similarity%20C-17.pdf; https://repository.unair.ac.id/112897/; https://www.mdpi.com/1424-8247/14/7/615; https://doi.org/10.3390/ph14070615
• Institution: Universitas Airlangga

Bone defects and periodontal disease are pathological conditions that may become neglected diseases if not treated properly. Hydroxyapatite (HA), along with tricalcium phosphate and bioglass ceramic, is a biomaterial widely applied to orthopedic and dental uses. The in vivo performance of HA is dete...