Diabetes dance of persadia 1 effect on blood IL-6 level

• Main Authors: Wahyu Nur Pratiwi, -, Bambang Purwanto, -, Abdurachman, -
• Format: Article PeerReviewed
• Language: English; English; English
• Published: IOP Publishing Ltd. 2019
• Subjects: R Medicine (General); RA Public aspects of medicine
• Online Access: https://repository.unair.ac.id/113460/2/6.%20Artikel.pdf; https://repository.unair.ac.id/113460/3/6.%20Similarity.pdf; https://repository.unair.ac.id/113460/6/peer%20review%2007.pdf; https://repository.unair.ac.id/113460/; https://iopscience.iop.org/article/10.1088/1742-6596/1146/1/012014
• Institution: Universitas Airlangga

Diabetes dance of Persadia 1 is the evolvement of prior diabetes dance series with aerobic principle and belong to weight bearing exercise with eccentric movement. The aim is to analyze the effect of Diabetes dance of Persadia 1 on blood level of IL-6.16 subjects of healthy housewifes who was participated and divided on 2 groups, exercise group and control group. Exercise group was given with diabetes dance of Persadia 1, 3 times per week, while control group have the unstructured activity. Blood level of IL-6 has been measured from each subject's blood that has taken after 24 hours post single bout exercise (acute-AE) and after repeated exercise (chronic exercise-CE). Paired t-test analysis on both acute (p = 0.674) and chronic (p = 0.949) shows blood level of IL-6 increase on control group post test result, though its not significant, while it has been decrease significantly on exercise group both AE (p = 0.000) and CE (p = 0.000). This happen because the stimulation of endogenous antioxidant production that is gluthatione, thus lowering oxidative stress biomarkers by suppressing H2O2 production, resulting in NFkB inhibition. NFkB inhibition will decrease the production of IL-6 muscle. This study shows that diabetes dance of Persadia 1 is not increasing blood levels of IL-6.