Effect of alpha tocopherol supplementation on tumor necrosis factor-alpha expression in human bone marrow mesenchymal stem cell (in vitro study)

• Main Authors: Wayan Sutresna Yasa, -, Ni Putu Mira Sumarta, -, Fredy Mardiyantoro, -, Purwati, -, Coen Pramono, -
• Format: Article PeerReviewed
• Language: English; English; Indonesian; Indonesian; English
• Published: Global Sciense Publications 2018
• Subjects: R Medicine; RK Dentistry
• Online Access: https://repository.unair.ac.id/113582/1/3%20EFFECT%20OF%20ALPHA%20TOCOPHEROL%20SUPPLEMENTATION.pdf; https://repository.unair.ac.id/113582/2/3_%20EFFECT%20OF%20ALPHA%20TOCOPHEROL%20SUPPLEMENTATION%20ON%20TUMOR%20NECROSIS%20FACTOR-ALPHAEXPRESSION%20IN%20HUMAN%20BONE%20MARROW%20MESENCHYMAL%20STEM%20CELL%20%28IN%20VITRO%20STUDY%29.pdf; https://repository.unair.ac.id/113582/3/3%20EFFECT%20OF%20ALPHA%20TOCOPHEROL%20SUPPLEMENTATION-validasi.pdf; https://repository.unair.ac.id/113582/6/Artikel%207%20Andra%20Rizqiawan.pdf; https://repository.unair.ac.id/113582/7/3.pdf; https://repository.unair.ac.id/113582/
• Institution: Universitas Airlangga

Inflammatory processes started first before osteogenic differentiation begin. Tumor necrosis factor lpha (TNF-) is a major pro-inflammatory cytokine, the over expression of which may prolong inflammation which may inhibit initiation of bone healing. It is beneficial in suppressing damaging effects...