Phytoconstituents of Genus Micromelum and Their Bioactivity—a Review

• Main Authors: Tin Myo Thant1, .-, Nanik Siti Aminah, .-, Alfinda Novi Kristanti, .-, Rico Ramadhan, .-, Hnin Thanda Aung, .-, Yoshiaki Takaya, .-
• Format: Article PeerReviewed
• Language: English; English; English
• Published: SAGE Journals 2020
• Subjects: Q Science; Q Science (General); QD Chemistry
• Online Access: https://repository.unair.ac.id/113729/1/C14.%20Fulltext.pdf; https://repository.unair.ac.id/113729/2/C14.%20Validasi%20dan%20review.pdf; https://repository.unair.ac.id/113729/3/C14.%20Similarity.pdf; https://repository.unair.ac.id/113729/; https://journals.sagepub.com/doi/pdf/10.1177/1934578X20927124
• Institution: Universitas Airlangga

The genus Micromelum belongs to the Rutaceae family. As its rich bioactive constituents its stems, flowers, leaves, and roots have been used in traditional medicine, for the treatment of various diseases from ancient time. Phytochemically, many bioactive compounds, including coumarins, polyoxygenated flavonoids, phenylpropanoic acid derivatives, quinolone alkaloids, and also carbazole alkaloids, have been reported as secondary metabolites of the Micromelum spp. including many new compounds. Therefore, Micromelum spp. are considered potential for drug leads. In this article, we present an overview of secondary metabolites isolated from genus Micromelum and their bioactivities that have been reported between 1982 and 2019.