Acceleration of post-tooth extraction socket healing after continuous aerobic and anaerobic physical exercise in Wistar rats (Rattus norvegicus)

• Main Authors: Aqsa Sjuhada Oki, -, Moch Febi Alviansyah, -, Christian Khoswanto, -, Retno Pudji Rahayu, -, Muhammad Luthfi, -
• Format: Article PeerReviewed
• Language: English; English; Indonesian; Indonesian; English; English; English
• Published: Fakultas Kedokteran Gigi Universitas Airlangga 2020
• Subjects: R Medicine; RK Dentistry
• Online Access: https://repository.unair.ac.id/114471/1/Acceleration%20of%20post-tooth%20extraction%20socket%20healing%20after%20continuous%20aerobic%20and%20anaerobic.pdf; https://repository.unair.ac.id/114471/3/12.1Acceleration%20of%20post-tooth%20extraction%20socket%20healing%20after%20continuous%20aerobic%20and%20anaerobic%20physical%20exercise%20in%20wistar%20rats%20%28Rattus%20norvegicus%29.pdf; https://repository.unair.ac.id/114471/2/12.Dr.Luthfi%20%28Acceleration%20of%20Post...%29.pdf; https://repository.unair.ac.id/114471/6/Peer%20Review%20%26%20validasi%209.pdf; https://repository.unair.ac.id/114471/7/11.%20Kualitas%20Karil%20dan%20Kesesuaian%20Bidang%20Ilmu.pdf; https://repository.unair.ac.id/114471/9/Acceleration.pdf; https://repository.unair.ac.id/114471/10/Acceleration.pdf; https://repository.unair.ac.id/114471/
• Institution: Universitas Airlangga

Background: Physical exercise has been proven to accelerate wound healing. Physical training itself consists of aerobic (continuous training) and anaerobic (interval training) exercise. The effectiveness of continuous physical exercise on post-tooth extraction wound healing is the focus of this study. Purpose: This study aims to investigate the differences in post-tooth extraction wound healing in Wistar rats (Rattus norvegicus) after aerobic and anaerobic exercise based on the number of fibroblasts and neovascularisation. Methods: Wistar rats were divided into three groups: the control group (K1); K2 undertook continuous aerobic exercise, swimming at 50% maximum swimming capacity (MSC) with an additional 3% bodyweight load; K3 undertook anaerobic continuous exercise, swimming at 65% MSC with a 6% load. The rats swam three times per week for six weeks. The number of fibroblasts and neovascularisation were examined three days after tooth extraction. Data was analysed using the one-way analysis of variance (ANOVA) and Least Significant Difference (LSD) tests (p<0.05). Results: There was a significant difference in the number of fibroblasts between the K2 and K3 groups. There was no significant difference between K2 and K3 in the amount of neovascularisation. Conclusion: There were differences in the number of fibroblasts but not neovascularisation after tooth extraction in Wistar rats given aerobic and anaerobic continuous training.