Artopeden A, a New Antiplasmodial Isoprenylated Flavone from Artocarpus champeden

• Main Authors: Tutik Sri Wahyuni, -, Wiwied Ekasari, -, Aty Widyawaruyanti, -, Yusuke Hirasawa, -, Hiroshi Morita, -, Noor Cholies Zaini, -
• Format: Article PeerReviewed
• Language: English; English; English
• Published: Japan Institute of Heterocyclic Chemistry 2009
• Subjects: R Medicine; RS Pharmacy and materia medica; RS1-441 Pharmacy and materia medica; RS200-201 Pharmaceutical dosage forms
• Online Access: https://repository.unair.ac.id/116540/1/C-11_artikel.pdf; https://repository.unair.ac.id/116540/2/C-11_peer%20review.pdf; https://repository.unair.ac.id/116540/3/C-11_similarity.pdf; https://repository.unair.ac.id/116540/; https://www.heterocycles.jp/newlibrary/libraries/abst/20384
• Institution: Universitas Airlangga

A new isoprenylated flavone, artopeden A (1) was isolated from the barks of Artocarpus champeden (Moraceae), and the structure was elucidated by NMR spectral analysis. Artopeden A (1) showed a potent antiplasmodial activity with an IC50 of 0.045 μg/mL against Plasmodium falciparum 3D7.