Correlation Oral Hairy Leukoplakia and CD4+ Counts in HIV/AIDS Patient at Dr. Soetomo Hospital Surabaya, Indonesia 2014

• Main Authors: Adiastuti Endah Parmadiati, -, Diah Savitri Ernawati, -, Bagus Soebadi, -, Alexander Patera Nugraha, -, Erwin Asta Triyono, -, Remita Adya Prasetyo, -, Sulistyowati Budi, -
• Format: Article PeerReviewed
• Language: English; English; English
• Published: Ektodermal Displazi Grubu 2017
• Subjects: RK Dentistry; RK1-715 Dentistry
• Online Access: https://repository.unair.ac.id/116805/1/1.Correlation%20Oral%20Hairy%20Leukoplakia%20and%20CD4%20Counts%20in%20HIVAIDS%20Patient%20at%20Dr.%20Soetomo%20Hospital%20Surabaya%2C%20Indonesia%202014.pdf; https://repository.unair.ac.id/116805/2/1.Correlation%20Oral%20Hairy%20Leukoplakia%20and%20CD4%2B%20Counts%20in%20HIV_AIDS%20Patients%20at%20Dr.%20Soetomo%20Hospital%20Surabaya%2C%20Indonesia%202014_compressed.pdf; https://repository.unair.ac.id/116805/5/1.%20correlation%20Oral%20Hairy%20Leukoplakia-dikompresi.pdf; https://repository.unair.ac.id/116805/; https://www.researchgate.net/publication/317027411_Correlation_oral_hairy_leukoplakia_and_CD4_counts_in_HIVAIDS_patients_at_Dr_soetomo_hospital_Surabaya_Indonesia_2014
• Institution: Universitas Airlangga

Indonesia is a one of the countries in South East Asia with a high prevalence of HIV/AIDS cases. Oral Hairy Leukoplakia (OHL) is the one of the oral manifestations that often found in HIV/AIDS patient decreased CD4+ counts. OHL play an important role and it can be used as a clinical biomarker to determine the stage, progression, predict the onset of opportunistic diseases and a strong indicator of immunodeficiency condition. The aim of this study to investigate correlation OHL and CD4+ counts in HIV/AIDS patients at UPIPI RSUD DR. Soetomo Surabaya 2014. This study was an analytic observational study with cross-sectional and total sampling method was conductet at UPIPI RSUD Dr. Soetomo. The samples consisted of 88 HIV/AIDS patients from July-August 2014. Diagnosed of OHL based on clinical appearance, the oral cavity of research subjects examined by oral medicine specialist. CD4+ counts obtained from patient’s medical record. 88 HIV/AIDS patients were examined; there were 15 patients with OHL (17,05%). OHL was found to be significantly correlated to decreased of CD4+ counts <200 cells/mm3 (p < 0.05). Decreased of CD4+ counts affect the occurrence of OHL. OHL may be used as an alternative to CD4 count to diagnose the immunodeficiency HIV/AIDS patients. Clinical article (J Int Dent Med Res 2017; 10: (1), pp. 162-165) Keywords: Oral Hairy Leukoplakia, HIV/AIDS, CD4+, Clinical Biomarker, Oral Manifestation. Received date: 14 March 2017 Accept date: 29 March 2017