Histomorphometric Analysis of Anti-Aging Properties on Rat Skin

We present a histomorphometric analysis to enable quantitative measurement of anti-aging activity of topical substances in rat skin. In this method, the measured parameters were closely related to changes that occur on the skin caused by exposure to UV light. We used this protocol to determine the a...

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Main Authors: Idha Kusumawati, -, Kresma Oky Kurniawan, -, Subhan Rullyansyah, -, Eka Pramyrtha Hestianah, -
Format: Article PeerReviewed
Language:English
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Published: Humana Press 2020
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Online Access:https://repository.unair.ac.id/116983/1/C-05%20Artikel.pdf
https://repository.unair.ac.id/116983/7/C-5%20Kualitas%20Karil.pdf
https://repository.unair.ac.id/116983/3/C-05%20Similarity.pdf
https://repository.unair.ac.id/116983/2/C-05%20korespondensi.pdf
https://repository.unair.ac.id/116983/
https://link.springer.com/protocol/10.1007/978-1-0716-0471-7_22
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Institution: Universitas Airlangga
Language: English
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Summary:We present a histomorphometric analysis to enable quantitative measurement of anti-aging activity of topical substances in rat skin. In this method, the measured parameters were closely related to changes that occur on the skin caused by exposure to UV light. We used this protocol to determine the anti-aging activities of an ethanolic extract of Curcuma heyneana rhizome and retinoic acid by a measurement of the changes in epidermal thickness, the number of sunburned cells, the number of fibroblasts, and the space between collagen fibers.