Aphrodisiac Activity of Ethanolic Extracts from the Fruits of Three Pepper Plants from Piperaceae Family
Background: Pepper plants belong to the Piperaceae family with many pharmacological activities. The fruits of these plants have been widely used traditionally for various therapies, one of which is an aphrodisiac. Objective: The purpose of this study was to determine the aphrodisiac activity of...
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Fakultas Farmasi Universitas Airlangga
2021
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id-langga.1170182023-03-26T07:49:53Z https://repository.unair.ac.id/117018/ Aphrodisiac Activity of Ethanolic Extracts from the Fruits of Three Pepper Plants from Piperaceae Family Idha Kusumawati, - Syailendra Mahatmaputra, - Rohman Hadi, - Rohmania, - Subhan Rullyansyah, - Helmy Yusuf, - Abdul Rahman, - R Medicine RS Pharmacy and materia medica RS1-441 Pharmacy and materia medica RS200-201 Pharmaceutical dosage forms Background: Pepper plants belong to the Piperaceae family with many pharmacological activities. The fruits of these plants have been widely used traditionally for various therapies, one of which is an aphrodisiac. Objective: The purpose of this study was to determine the aphrodisiac activity of the fruits of three pepper plants, Piper nigrum, Piper retrofractum, and Piper cubeba to prove their traditional use. Methods: The level of piperin, the active compound of plants from the family Piperaceae, was also determined in the ethanolic extract of those three fruits of the pepper plant. The aphrodisiac activity was determined by counting the number of introducing and mounting mice. The acute toxicity test of the extract was carried out according to the OECD-423 guidelines. Results: The ethanolic extract of Piper nigrum fruits had the highest piperin concentration, while the ethanolic extract of Piper retrofractum fruits had the highest aphrodisiac activity, according to the findings. During the entire duration of the acute toxicity study, no signs of toxicity or mortality were discovered. Conclusion: This study proves that all fruits of three species of pepper plants exhibit aphrodisiac activity. Furthermore, this study also shows that not only piperin is responsible for the aphrodisiac effect. Fakultas Farmasi Universitas Airlangga 2021-08-21 Article PeerReviewed text en https://repository.unair.ac.id/117018/1/C-27%20Artikel.pdf text en https://repository.unair.ac.id/117018/5/C-27%20Kualitas%20Karil.pdf text en https://repository.unair.ac.id/117018/2/C-27%20korespondensi.pdf Idha Kusumawati, - and Syailendra Mahatmaputra, - and Rohman Hadi, - and Rohmania, - and Subhan Rullyansyah, - and Helmy Yusuf, - and Abdul Rahman, - (2021) Aphrodisiac Activity of Ethanolic Extracts from the Fruits of Three Pepper Plants from Piperaceae Family. Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 8 (2). pp. 194-199. ISSN 2580-8303 https://www.e-journal.unair.ac.id/JFIKI/article/view/27523 https://doi.org/10.20473/jfiki.v8i22021.194-199 |
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R Medicine RS Pharmacy and materia medica RS1-441 Pharmacy and materia medica RS200-201 Pharmaceutical dosage forms |
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R Medicine RS Pharmacy and materia medica RS1-441 Pharmacy and materia medica RS200-201 Pharmaceutical dosage forms Idha Kusumawati, - Syailendra Mahatmaputra, - Rohman Hadi, - Rohmania, - Subhan Rullyansyah, - Helmy Yusuf, - Abdul Rahman, - Aphrodisiac Activity of Ethanolic Extracts from the Fruits of Three Pepper Plants from Piperaceae Family |
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Background: Pepper plants belong to the Piperaceae family with many pharmacological activities. The fruits of these plants have been widely used traditionally for various therapies, one of which is an aphrodisiac.
Objective: The purpose of this study was to determine the aphrodisiac activity of the fruits of three pepper plants, Piper nigrum, Piper retrofractum, and Piper cubeba to prove their traditional use. Methods: The level of piperin, the active compound of plants from the family Piperaceae, was also determined in the ethanolic extract of those three fruits of the pepper plant. The aphrodisiac activity was determined by counting the number of introducing and mounting mice. The acute toxicity test of the extract was carried out according to the OECD-423 guidelines.
Results: The ethanolic extract of Piper nigrum fruits had the highest piperin concentration, while the ethanolic extract of Piper retrofractum fruits had the highest aphrodisiac activity, according to the findings. During the entire duration of the acute toxicity study, no signs of toxicity or mortality were discovered.
Conclusion: This study proves that all fruits of three species of pepper plants exhibit aphrodisiac activity. Furthermore, this study also shows that not only piperin is responsible for the aphrodisiac effect. |
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Article PeerReviewed |
author |
Idha Kusumawati, - Syailendra Mahatmaputra, - Rohman Hadi, - Rohmania, - Subhan Rullyansyah, - Helmy Yusuf, - Abdul Rahman, - |
author_facet |
Idha Kusumawati, - Syailendra Mahatmaputra, - Rohman Hadi, - Rohmania, - Subhan Rullyansyah, - Helmy Yusuf, - Abdul Rahman, - |
author_sort |
Idha Kusumawati, - |
title |
Aphrodisiac Activity of Ethanolic Extracts from the Fruits of Three Pepper Plants from Piperaceae Family |
title_short |
Aphrodisiac Activity of Ethanolic Extracts from the Fruits of Three Pepper Plants from Piperaceae Family |
title_full |
Aphrodisiac Activity of Ethanolic Extracts from the Fruits of Three Pepper Plants from Piperaceae Family |
title_fullStr |
Aphrodisiac Activity of Ethanolic Extracts from the Fruits of Three Pepper Plants from Piperaceae Family |
title_full_unstemmed |
Aphrodisiac Activity of Ethanolic Extracts from the Fruits of Three Pepper Plants from Piperaceae Family |
title_sort |
aphrodisiac activity of ethanolic extracts from the fruits of three pepper plants from piperaceae family |
publisher |
Fakultas Farmasi Universitas Airlangga |
publishDate |
2021 |
url |
https://repository.unair.ac.id/117018/1/C-27%20Artikel.pdf https://repository.unair.ac.id/117018/5/C-27%20Kualitas%20Karil.pdf https://repository.unair.ac.id/117018/2/C-27%20korespondensi.pdf https://repository.unair.ac.id/117018/ https://www.e-journal.unair.ac.id/JFIKI/article/view/27523 https://doi.org/10.20473/jfiki.v8i22021.194-199 |
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1762032193000964096 |