Comparison of TLR2/1, NF-кB p105/50, NF-кB p65, and TNF-α expressions in the macrophages between multibacillary leprosy patients with and without erythema nodosum leprosum signifying innate immune system activity

• Main Authors: M. Yulianto Listiawan, -, Cita Rosita Sigit Prakoeswa, -, Indropo Agusni, -
• Format: Article PeerReviewed
• Language: English; English; English; English
• Published: Sanglah General Hospital 2019
• Subjects: R Medicine (General); RL Dermatology
• Online Access: https://repository.unair.ac.id/119599/1/Artikel.pdf; https://repository.unair.ac.id/119599/2/Bukti%20korespondensi.pdf; https://repository.unair.ac.id/119599/3/Karil.pdf; https://repository.unair.ac.id/119599/4/Similarity.pdf; https://repository.unair.ac.id/119599/; https://www.balimedicaljournal.org/index.php/bmj/article/view/1482; https://doi.org/10.15562/bmj.v8i1.1482
• Institution: Universitas Airlangga

Background: Erythema nodosum leprosum (ENL) is one of the complications in multibacillary (MB) leprosy. The cause, mechanism, and treatment of ENL remain highly problematic. Various studies have identified possible involvement of the innate immune system in the pathogenesis of ENL. Increased underst...