Success Of Syphilis Therapy In Hiv/Aids Patients Related To Cd4 Level

• Main Authors: Andre Yuindartanto, Andre, Afif Nurul Hidayati, Afif, Diah Mira Indramaya, Diah, M. Yulianto Listiawan, -, Evy Ervianti, Evy, Damayanti, Damayanti, Erwin Astha Triyono, Erwin
• Format: Article PeerReviewed
• Language: English; English; Indonesian; English; English; English; Indonesian
• Published: Badebio Biotechnololgy Ltd 2022
• Subjects: R5-920 Medicine (General)
• Online Access: https://repository.unair.ac.id/120065/1/05.%20turnitin.pdf; https://repository.unair.ac.id/120065/2/05.%20artikel.pdf; https://repository.unair.ac.id/120065/3/05.%20karil.pdf; https://repository.unair.ac.id/120065/6/18.pdf; https://repository.unair.ac.id/120065/7/Bukti%20Korespondensi%2018.pdf; https://repository.unair.ac.id/120065/9/9%20%281%29.pdf; https://repository.unair.ac.id/120065/11/10.%20Success%20Of%20Syphilis%20Therapy%20In%20Hiv%20Aids%20Patients%20Related%20To%20Cd4%20Level.pdf; https://repository.unair.ac.id/120065/; https://www.nveo.org/index.php/journal/article/view/4568
• Institution: Universitas Airlangga

Background: Syphilis and human immunodeficiency virus (HIV) infection are diseases that can be transmitted through sexual intercourse, so it is not surprising that someone has both at the same time. Syphilis can increase the risk of contracting the Human immunodeficiency virus (HIV) where HIV-negative people exposed to syphilis will increase the risk of contracting up to 3-5 times. Objective: This study aims to determine the success of syphilis therapy in HIV/AIDS patients related to CD4 levels. Methods: This study was conducted using a quantitative analytic design, the type of research carried out was retrospective by collecting data that had been collected previously. The population in this study were all patients with HIV in Dr. Hospital. Soetomo Surabaya. The sample in this study was selected using a total sampling technique involving 25 people with HIV. The data of this study were sourced from secondary data, namely medical record data from the inpatient and outpatient of UPIPI RSUD Dr. Soetomo Surabaya in 2019. The CD4 levels obtained were analyzed by descriptive statistical tests and T-tests, while Duncan's test was used to determine VDRL levels. Results: The results of this study indicate that syphilis therapy has been shown to increase CD4 levels. This increase was obtained based on the results of calculations before and before syphilis therapy. An increase in CD4 cells in HIV patients through syphilis therapy was also accompanied by a decrease in VDRL. Based on the test results, it is known that there are significant differences before and before therapy where VDRL decreases every time the experiment starts from 1st titer to 4th titer with the average obtained (1st titer = 11.04), (2nd titer = 4.72), (3rd titer = 4.08) and (4th titer = 1.84). Conclusion: Syphilis therapy has been shown to be able to increase CD4 levels in syphilis patients with HIV and reduce VDRL levels.