Profile of cardiovascular disease risk in type 2 diabetes mellitus patients receiving statin therapy: A cross-sectional study
Abstract Background: Cardiovascular disease is still the number 1 cause of death globally. Meanwhile, type 2 diabetes mellitus (T2DM) is a risk factor for atherosclerosis vascular disease (ASCVD), so an assessment using Framingham Risk Score (FRS) is needed to predict the risk of ASCVD in the futur...
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| Main Authors: | , , |
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| Format: | Article PeerReviewed |
| Language: | English English Indonesian |
| Published: |
Elsevier
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| Online Access: | https://repository.unair.ac.id/120132/1/13%20artikel.pdf https://repository.unair.ac.id/120132/2/13%20turnitin.pdf https://repository.unair.ac.id/120132/3/13%20karil.pdf https://repository.unair.ac.id/120132/ https://www.sciencedirect.com/science/article/pii/S2049080122001285?via%3Dihub https://doi.org/10.1016/j.amsu.2022.103368 |
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| Institution: | Universitas Airlangga |
| Language: | English English Indonesian |
| Summary: | Abstract
Background: Cardiovascular disease is still the number 1 cause of death globally. Meanwhile, type 2 diabetes mellitus (T2DM) is a risk factor for atherosclerosis vascular disease (ASCVD), so an assessment using Framingham Risk Score (FRS) is needed to predict the risk of ASCVD in the future.
Objective: Analyzing the risk factor of ASCVD using the Framingham Risk Score (FRS) in T2DM patients.
Methods: This study was conducted from July 2020 to July 2021, which the participants were measured for FRS including age, gender, current smoking, diabetes, blood pressure (systolic), high-density lipoprotein (HDL) cholesterol, total cholesterol (TC), and ASCVD risk score. The analysis employed multiple linear tests and ANOVA tests with p < 0.05.
Results: Several ASCVD risk factors in T2DM patients were found, including gender (t = 6.015; p < 0.001), age (t = 6.901; p < 0.001), HDL level (t = 2.287; p = 0.024), CT level (t = 5.273; p < 0.001), blood pressure (t = 5.850; p < 0.001), and current smoking (t = 2.638; p = 0.009). The results of analysis between ASCVD risk factor and level of ASCVD risk obtained a significant association (F = 36,642; p < 0.001).
Conclusion: Risk factors of ASCVD in T2DM patients such as gender, age, HDL level, CT level, blood pressure, and current smoking. |
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