Dexamethasone and olmesartan as potential antiremodelling agents of valvular interstitial cell into myofibroblast: In vitrostudy on β-smooth muscle actin expression

• Main Authors: Ardianto Nandiwardhana, Ardianto, Denny Suwanto, Denny, Eka Prasetya Budi Mulia, Eka, David Nugraha, David, Achmad Lefi, Achmad, Mohammad Budiarto, Mohammad, Johanes Nugroho Eko Putranto, Johanes
• Format: Article PeerReviewed
• Language: English; English; Indonesian
• Published: Universidad Tecnica de Manabi
• Subjects: R5-920 Medicine (General)
• Online Access: https://repository.unair.ac.id/120141/1/24%20artikel.pdf; https://repository.unair.ac.id/120141/2/24%20turnitin.pdf; https://repository.unair.ac.id/120141/3/24%20karil.pdf; https://repository.unair.ac.id/120141/; https://sciencescholar.us/journal/index.php/ijhs/article/view/12283; https://doi.org/10.53730/ijhs.v6nS9.12283
• Institution: Universitas Airlangga

Abstract Rheumatic heart disease is a late complication of valvular inflammation caused by rheumatic fever. Studies have shown that the differentiation of valvular interstitial cells (VIC) into fibroblasts plays an important role in valvular remodeling and fibrosis. Various strategies to minimize v...