Risk Factors For Disability In Leprosy Patients: A Cross-Sectional Study
Abstract Background: The disability in leprosy is caused by M. leprae invasion and infiltration into the skin and the mucous membrane that results in nerve damage and deformities, loss of sensation, paralysis, and ocular manifestation. The risk of disability can be influenced by several factors, in...
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id-langga.1212242023-05-09T00:59:19Z https://repository.unair.ac.id/121224/ Risk Factors For Disability In Leprosy Patients: A Cross-Sectional Study Silvani Geani, Silvani Rahmadewi, Rahmadewi Astindari, Astindari Cita Rosita Sigit Prakoeswa, Cita Sawitri, Sawitri Evy Ervianti, Evy Budi Utomo, Budi Medhi Denisa, Medhi Novianti Rizky Reza, Novianti Bagus Haryo Kusumaputra, Bagus Regitta Indira Agusni, Regitta Putri Hendria Wardhani, Putri Muhammad Yulianto Listiawan, Muhammad R5-920 Medicine (General) Abstract Background: The disability in leprosy is caused by M. leprae invasion and infiltration into the skin and the mucous membrane that results in nerve damage and deformities, loss of sensation, paralysis, and ocular manifestation. The risk of disability can be influenced by several factors, including the type of leprosy, disease duration, the number of nerves affected, leprosy reactions, gender, age, type of treatment, socioeconomic factors, and leprosy case detection methods. This study aimed to evaluate the risk factor of disability in leprosy patients. Methods: It was a cross-sectional retrospective analytical study to discover the correlation between risk factors with the grade of disability in leprosy patients who were treated in Dermatovenerology Outpatient Clinic Dr. Soetomo General Hospital Surabaya from 2017 to 2019. Result: This study found a total of 275 leprosy patients with disabilities, consisting of 76 patients (27,6%) with grade-1 disability and 199 patients (72,4%) with grade 2 disability. There was a statistically significant correlation between age (p=0,025), duration of disease (p=0,001), and multidrug therapy (MDT) history (p=0,001) with the incidence of disability. Gender, bacterial index, type of leprosy, and leprosy reaction were not significantly related to disability. Conclusion: This study showed that age, duration of disease, and the history of MDT treatment were related to the incidence of disability. The longer the disease's duration despite the patient having received MDT, the more risk of the patient having a disability. Sanglah General Hospital Article PeerReviewed text en https://repository.unair.ac.id/121224/1/30%20artikel.pdf text en https://repository.unair.ac.id/121224/2/30%20turnitin.pdf text id https://repository.unair.ac.id/121224/3/30%20karil.pdf text en https://repository.unair.ac.id/121224/6/3.pdf Silvani Geani, Silvani and Rahmadewi, Rahmadewi and Astindari, Astindari and Cita Rosita Sigit Prakoeswa, Cita and Sawitri, Sawitri and Evy Ervianti, Evy and Budi Utomo, Budi and Medhi Denisa, Medhi and Novianti Rizky Reza, Novianti and Bagus Haryo Kusumaputra, Bagus and Regitta Indira Agusni, Regitta and Putri Hendria Wardhani, Putri and Muhammad Yulianto Listiawan, Muhammad Risk Factors For Disability In Leprosy Patients: A Cross-Sectional Study. Bali Medical Journal, 11 (1). pp. 197-201. ISSN P-ISSN : 2089-1180, E-ISSN : 2302-12914 https://www.balimedicaljournal.org/index.php/bmj/article/view/3311#:~:text=The%20risk%20of%20disability%20can,and%20leprosy%20case%20detection%20methods. https://doi.org/10.15562/bmj.v11i1.3311 |
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R5-920 Medicine (General) Silvani Geani, Silvani Rahmadewi, Rahmadewi Astindari, Astindari Cita Rosita Sigit Prakoeswa, Cita Sawitri, Sawitri Evy Ervianti, Evy Budi Utomo, Budi Medhi Denisa, Medhi Novianti Rizky Reza, Novianti Bagus Haryo Kusumaputra, Bagus Regitta Indira Agusni, Regitta Putri Hendria Wardhani, Putri Muhammad Yulianto Listiawan, Muhammad Risk Factors For Disability In Leprosy Patients: A Cross-Sectional Study |
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Abstract
Background: The disability in leprosy is caused by M. leprae invasion and infiltration into the skin and the mucous membrane that results in nerve damage and deformities, loss of sensation, paralysis, and ocular manifestation. The risk of disability can be influenced by several factors, including the type of leprosy, disease duration, the number of nerves affected, leprosy reactions, gender, age, type of treatment, socioeconomic factors, and leprosy case detection methods. This study aimed to evaluate the risk factor of disability in leprosy patients.
Methods: It was a cross-sectional retrospective analytical study to discover the correlation between risk factors with the grade of disability in leprosy patients who were treated in Dermatovenerology Outpatient Clinic Dr. Soetomo General Hospital Surabaya from 2017 to 2019.
Result: This study found a total of 275 leprosy patients with disabilities, consisting of 76 patients (27,6%) with grade-1 disability and 199 patients (72,4%) with grade 2 disability. There was a statistically significant correlation between age (p=0,025), duration of disease (p=0,001), and multidrug therapy (MDT) history (p=0,001) with the incidence of disability. Gender, bacterial index, type of leprosy, and leprosy reaction were not significantly related to disability.
Conclusion: This study showed that age, duration of disease, and the history of MDT treatment were related to the incidence of disability. The longer the disease's duration despite the patient having received MDT, the more risk of the patient having a disability. |
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Silvani Geani, Silvani Rahmadewi, Rahmadewi Astindari, Astindari Cita Rosita Sigit Prakoeswa, Cita Sawitri, Sawitri Evy Ervianti, Evy Budi Utomo, Budi Medhi Denisa, Medhi Novianti Rizky Reza, Novianti Bagus Haryo Kusumaputra, Bagus Regitta Indira Agusni, Regitta Putri Hendria Wardhani, Putri Muhammad Yulianto Listiawan, Muhammad |
author_facet |
Silvani Geani, Silvani Rahmadewi, Rahmadewi Astindari, Astindari Cita Rosita Sigit Prakoeswa, Cita Sawitri, Sawitri Evy Ervianti, Evy Budi Utomo, Budi Medhi Denisa, Medhi Novianti Rizky Reza, Novianti Bagus Haryo Kusumaputra, Bagus Regitta Indira Agusni, Regitta Putri Hendria Wardhani, Putri Muhammad Yulianto Listiawan, Muhammad |
author_sort |
Silvani Geani, Silvani |
title |
Risk Factors For Disability In Leprosy Patients: A Cross-Sectional Study |
title_short |
Risk Factors For Disability In Leprosy Patients: A Cross-Sectional Study |
title_full |
Risk Factors For Disability In Leprosy Patients: A Cross-Sectional Study |
title_fullStr |
Risk Factors For Disability In Leprosy Patients: A Cross-Sectional Study |
title_full_unstemmed |
Risk Factors For Disability In Leprosy Patients: A Cross-Sectional Study |
title_sort |
risk factors for disability in leprosy patients: a cross-sectional study |
publisher |
Sanglah General Hospital |
url |
https://repository.unair.ac.id/121224/1/30%20artikel.pdf https://repository.unair.ac.id/121224/2/30%20turnitin.pdf https://repository.unair.ac.id/121224/3/30%20karil.pdf https://repository.unair.ac.id/121224/6/3.pdf https://repository.unair.ac.id/121224/ https://www.balimedicaljournal.org/index.php/bmj/article/view/3311#:~:text=The%20risk%20of%20disability%20can,and%20leprosy%20case%20detection%20methods. https://doi.org/10.15562/bmj.v11i1.3311 |
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1767194139655405568 |