Increased Activity Of Mature Osteoblast From Rat Bone Marrow-Mesenchymal Stem Cells In Osteogenic Medium Exposed To Melatonin

• Main Authors: Yugi Hari Chandra Purnama, Yugi, Gondo Mastutik, Gondo, Suhartono Taat Putra, Suhartono
• Format: Article PeerReviewed
• Language: English; Indonesian; Indonesian; English
• Published: Faculty of Medicine, Universitas Airlangga, Indonesia
• Subjects: R5-920 Medicine (General)
• Online Access: https://repository.unair.ac.id/121659/1/C17%20Artikel%20INCREASED%20ACTIVITY.pdf; https://repository.unair.ac.id/121659/2/C17%20Etik%20INCREASED%20ACTIVITY.pdf; https://repository.unair.ac.id/121659/3/C17%20PAK%201.pdf; https://repository.unair.ac.id/121659/4/C17%20Turnitin%20INCREASED%20ACTIVITY.pdf; https://repository.unair.ac.id/121659/; https://e-journal.unair.ac.id/FMI/article/view/10714/6890; https://doi.org/10.20473/fmi.v54i4.10714
• Institution: Universitas Airlangga

Abstract Exposure to melatonin in the cultures of Bone Marrow Mesenchymal Stem Cells (BM-MSCs) in osteogenic medium is able to induce mesenchymal stem cells and preosteoblasts into active osteoblasts via several transduction signals such as ERK 1/2. Previous studies used a single dose of 50 nM and...