Effect of Andrographolide and Resveratrol on OX1R and Prepro-orexin mRNA expression in CIPN-induced hypothalamus of mice with oxaliplatin

• Main Authors: Chrismawan Ardianto, -, Ardian Lestari Judoko, -, Mirza Aprilia, -, Dinda Monika Nusantara Ratri, -, Toetik Ariyani, -, Mahardian Rahmadi, -, Junaidi Khotib, -
• Format: Article PeerReviewed
• Language: English; English; English; English; English; English
• Published: A and V Publication 2022
• Subjects: R Medicine; RS Pharmacy and materia medica; RS1-441 Pharmacy and materia medica; RS200-201 Pharmaceutical dosage forms
• Online Access: https://repository.unair.ac.id/123550/1/C-14%20Artikel.pdf; https://repository.unair.ac.id/123550/7/C-14%20Kualitas%20Karil.pdf; https://repository.unair.ac.id/123550/3/C-14%20Similariy.pdf; https://repository.unair.ac.id/123550/9/Artikel%20C-4.pdf; https://repository.unair.ac.id/123550/10/%28C-04%29%20Kualitas%20Karil.pdf; https://repository.unair.ac.id/123550/11/Similarity%20C-4.pdf; https://repository.unair.ac.id/123550/; https://www.rjptonline.org/AbstractView.aspx?PID=2022-15-10-73; https://doi.org/10.52711/0974-360X.2022.00800
• Institution: Universitas Airlangga

Chemotherapy-induced peripheral neuropathy (CIPN) is a one of side effect in cancer patients that receive antineoplastic agent, like oxaliplatin. Orexinergic system in the hypothalamus is the one of system that modulate nociceptive and neuropathy. Because there is flavonoids such as resveratrol and...