Comparison of the Effect of Calcium Hydroxide Combination with Cocoa Pod Husk Extract and Green Tea Extract On C-Fos and Dmp-1 Expression in Exposed Dental Pulp
Dental caries is still a worldwide problem including in Indonesia. Untreated caries may progress into deep lesion cause abnormalities in the pulp that can be reversible or irreversible. Direct pulp capping is one of the treatments of an exposed vital pulp due to caries, caries removal, and trauma....
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| Main Authors: | , , , , , , |
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| Format: | Article PeerReviewed |
| Language: | English English English English English |
| Published: |
2022
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| Subjects: | |
| Online Access: | https://repository.unair.ac.id/123699/1/11.pdf https://repository.unair.ac.id/123699/2/11.pdf https://repository.unair.ac.id/123699/3/11.pdf https://repository.unair.ac.id/123699/4/11.pdf https://repository.unair.ac.id/123699/8/11.DENTALPULP.pdf https://repository.unair.ac.id/123699/ |
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| Institution: | Universitas Airlangga |
| Language: | English English English English English |
| Summary: | Dental caries is still a worldwide problem including in Indonesia. Untreated caries may progress
into deep lesion cause abnormalities in the pulp that can be reversible or irreversible. Direct pulp
capping is one of the treatments of an exposed vital pulp due to caries, caries removal, and trauma.
Calcium hydroxide has been the gold standard as pulp capping materials in pulp protection but it
does have some disadvantages. To overcome these disadvantages the research was carried out
with other alternative materials for direct pulp capping using natural material. To analyze the effect
of calcium hydroxide mixed with cocoa pod husk extract and calcium hydroxide mixed with green
tea extract on c-FOS and DMP-1 expression in mice perforation dental pulp.
Sixty upper molars in Wistar rats were perforated mechanically and applied the combination
material of pulp capping then divided into three groups. The control group were treated with calcium
hydroxide and distilled water The treatment groups were treated with calcium hydroxide with cocoa
pod husk extract and calcium hydroxide mixed with green tea extract.
The treatment group of calcium hydroxide with green tea extract increased the expression of cFOS and DMP-1 more than the treatment group of calcium hydroxide with cocoa pod husk extract,
there were no statistically significant differences between groups.
Both cocoa and green tea mixed with calcium hydroxide have relatively the same antiinflammatory and antioxidant properties so their active substances have the effect same effect to
increase the number of c-FOS dan DMP- 1 expressions in mice perforation dental pulp. |
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