The Effect of Cocoa Pod Husk and Green Tea Extract on SMAD3 and FGF2 Expressions in Exposed Dental Pulp

• Main Authors: Tamara Yuanita, -, Irfan Prasetyo, -, I Dewa Ayu Listiana, -, Irma Drismayanti, -, Nawira, -, Galih Sampoerno, -, Sukaton, -
• Format: Article PeerReviewed
• Language: English; English; English; English; English
• Published: Ektodermal Displazi Grubu 2022
• Subjects: RK Dentistry
• Online Access: https://repository.unair.ac.id/123704/1/13.pdf; https://repository.unair.ac.id/123704/2/13.pdf; https://repository.unair.ac.id/123704/3/13.pdf; https://repository.unair.ac.id/123704/6/1.pdf; https://repository.unair.ac.id/123704/8/13.COCOA%20POD.pdf; https://repository.unair.ac.id/123704/; http://www.jidmr.com/journal/contents-of-jidmr- 2022-vol-15-no-1/
• Institution: Universitas Airlangga

Direct pulp capping employing calcium hydroxide has been used to maintain the pulp’s vitality and health and encourage the pulp cells to establish reparative dentin. It has been recommended to use calcium hydroxide as a material of direct pulp capping due to its beneficial properties. However, calcium hydroxide also has several weaknesses. Cocoa pod husks and green tea contain high polyphenols which are useful for their antibacterial, anti-inflammatory, and antioxidant properties. The extracts of cocoa pod husk and green tea combined with calcium hydroxide are expected to increase the effectiveness of calcium hydroxide as a pulp capping material. Objectives to prove the extracts of cocoa pod husk and green tea’s effects on the SMAD3 and FGF2 expressions in mice with perforated dental pulps. A total of 54 rats were used and divided into three groups: given calcium hydroxide treatment with distilled water, calcium hydroxide with the extract of cocoa pod husk, and calcium hydroxide with the extract of green tea. Then, cavities were then restored. The experimental animals from each treatment group were killed on days 3, 7, and 14 to observe their SMAD3 and FGF2 expressions. Data analysis with the Tukey HSD test for SMAD3 and FGF2 expressions on the two test groups suggested no significant difference. The extracts of cocoa pod husk and green tea have the same ability to increase the SMAD3 and FGF2 expression in exposed dental pulp.