Combination of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) on woven bone area post tooth extraction
Background: Tooth extraction is one of the most frequently performed procedures in dental practice. Resorption without bone regeneration can change the maxillary and mandibular bone structure, resulting lack of retention, stability, and comfort of the denture. Hence, adequate regeneration of alveola...
Saved in:
Main Authors: | , , |
---|---|
Format: | Article PeerReviewed |
Language: | English English Indonesian |
Published: |
WJARR
2023
|
Subjects: | |
Online Access: | https://repository.unair.ac.id/123791/1/A13.pdf https://repository.unair.ac.id/123791/2/T13.pdf https://repository.unair.ac.id/123791/3/13.pdf https://repository.unair.ac.id/123791/ |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Universitas Airlangga |
Language: | English English Indonesian |
id |
id-langga.123791 |
---|---|
record_format |
dspace |
spelling |
id-langga.1237912023-04-16T13:11:06Z https://repository.unair.ac.id/123791/ Combination of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) on woven bone area post tooth extraction Utari Kresnoadi, - Phara Aster Chandra Adventia, - Ratri Maya Sitalaksmi, - R Medicine RK Dentistry RK641-667 Prosthetic dentistry. Prosthodontics Background: Tooth extraction is one of the most frequently performed procedures in dental practice. Resorption without bone regeneration can change the maxillary and mandibular bone structure, resulting lack of retention, stability, and comfort of the denture. Hence, adequate regeneration of alveolar bone is considered an important factor for successful dentures. Moringa oleifera is a plant rich in flavonoids, saponins, alkaloids and tannins. Purpose: This study aims to find out the effect of induction from combination of Moringa oleifera extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) on woven bone area post tooth extraction procedure. Methods: Cavia cobaya was divided into eight groups, each group consists of seven. The lower incisors of Fifty-six Cavia cobaya were extracted. The first group (control group) was given polyethylene glycol, the second group with DFDBBX, the third group with Moringa leaf extract, and the fourth group with a combination of DFDBBX and Moringa leaf extract. Cavia cobaya were sacrificed on day 7 and 14. Histopathological examinations of woven bone area was observed under a 400x magnification light microscope. Kruskal-Wallis and Mann-Whitney tests were performed to analyze the data. Results: There was a significant difference in woven bone area between the groups (P<0.05). The highest mean of woven bone area was found in the combination group on both day 7 and 14. Conclusion: The combination of Moringa leaf extract and DFDBBX could effectively formed new woven bone during the alveolar bone regeneration. WJARR 2023 Article PeerReviewed text en https://repository.unair.ac.id/123791/1/A13.pdf text en https://repository.unair.ac.id/123791/2/T13.pdf text id https://repository.unair.ac.id/123791/3/13.pdf Utari Kresnoadi, - and Phara Aster Chandra Adventia, - and Ratri Maya Sitalaksmi, - (2023) Combination of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) on woven bone area post tooth extraction. World Journal of Advanced Research and Reviews, 17 (2). pp. 494-499. ISSN 2851-9615 10.30574/wjarr.2023.17.2.0225 |
institution |
Universitas Airlangga |
building |
Universitas Airlangga Library |
continent |
Asia |
country |
Indonesia Indonesia |
content_provider |
Universitas Airlangga Library |
collection |
UNAIR Repository |
language |
English English Indonesian |
topic |
R Medicine RK Dentistry RK641-667 Prosthetic dentistry. Prosthodontics |
spellingShingle |
R Medicine RK Dentistry RK641-667 Prosthetic dentistry. Prosthodontics Utari Kresnoadi, - Phara Aster Chandra Adventia, - Ratri Maya Sitalaksmi, - Combination of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) on woven bone area post tooth extraction |
description |
Background: Tooth extraction is one of the most frequently performed procedures in dental practice. Resorption without bone regeneration can change the maxillary and mandibular bone structure, resulting lack of retention, stability, and comfort of the denture. Hence, adequate regeneration of alveolar bone is considered an important factor for successful dentures. Moringa oleifera is a plant rich in flavonoids, saponins, alkaloids and tannins.
Purpose: This study aims to find out the effect of induction from combination of Moringa oleifera extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) on woven bone area post tooth extraction procedure.
Methods: Cavia cobaya was divided into eight groups, each group consists of seven. The lower incisors of Fifty-six Cavia cobaya were extracted. The first group (control group) was given polyethylene glycol, the second group with DFDBBX, the third group with Moringa leaf extract, and the fourth group with a combination of DFDBBX and Moringa leaf extract. Cavia cobaya were sacrificed on day 7 and 14. Histopathological examinations of woven bone area was observed under a 400x magnification light microscope. Kruskal-Wallis and Mann-Whitney tests were performed to analyze the data.
Results: There was a significant difference in woven bone area between the groups (P<0.05). The highest mean of woven bone area was found in the combination group on both day 7 and 14.
Conclusion: The combination of Moringa leaf extract and DFDBBX could effectively formed new woven bone during the alveolar bone regeneration. |
format |
Article PeerReviewed |
author |
Utari Kresnoadi, - Phara Aster Chandra Adventia, - Ratri Maya Sitalaksmi, - |
author_facet |
Utari Kresnoadi, - Phara Aster Chandra Adventia, - Ratri Maya Sitalaksmi, - |
author_sort |
Utari Kresnoadi, - |
title |
Combination of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) on woven bone area post tooth extraction |
title_short |
Combination of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) on woven bone area post tooth extraction |
title_full |
Combination of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) on woven bone area post tooth extraction |
title_fullStr |
Combination of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) on woven bone area post tooth extraction |
title_full_unstemmed |
Combination of Moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (DFDBBX) on woven bone area post tooth extraction |
title_sort |
combination of moringa oleifera leaf extract and demineralized freeze-dried bovine bone xenograft (dfdbbx) on woven bone area post tooth extraction |
publisher |
WJARR |
publishDate |
2023 |
url |
https://repository.unair.ac.id/123791/1/A13.pdf https://repository.unair.ac.id/123791/2/T13.pdf https://repository.unair.ac.id/123791/3/13.pdf https://repository.unair.ac.id/123791/ |
_version_ |
1764209122265268224 |