TRAP-positive osteoclast precursors mediate ROS/NOdependent bactericidal activity via TLR4

• Main Authors: Kazuaki Nishimura, -, Satoru Shindo, -, Alexandru Movila, -, Rayyan Kayal, -, Albassam Abdullah, -, Irma Josefina Savitri, -, Atsushi Ikeda, -, Tsuguno Yamaguchi, -, Mohammed Howait, -, Ayman Al-dharrab, -, Abdulghani Mira, -, Xiaozhe Han, -, Toshihisa Kawai, -
• Format: Article PeerReviewed
• Language: English; English; English
• Published: 2021
• Subjects: RK Dentistry
• Online Access: https://repository.unair.ac.id/124760/1/1.ARTIKEL.pdf; https://repository.unair.ac.id/124760/2/1.TURNITIN.pdf; https://repository.unair.ac.id/124760/3/1.pdf; https://repository.unair.ac.id/124760/
• Institution: Universitas Airlangga

Osteoclastogenesis was induced by RANKL stimulation in mouse monocytes to examine the possible bactericidal function of osteoclast precursors (OCp) and mature osteoclasts (OCm) relative to their production of NO and ROS. Tartrate-resistant acid phosphatase (TRAP)-positive OCp, but few or no OCm,...