Integrated Propranolol, Methylprednisolone, And Surgery In Managing A Rare Case Of Infantile Hemangioma With Concurrent Cleft Lip And Palate

• Main Authors: Ishandono Dachlan, Ishandono, Siti Isya Wahdini, Siti, Indri Lakhsmi Putri, Indri, Muhammad Rosadi Seswandhana, Muhammad, Aditya Wicaksana, Aditya, Aditya Rifqi Fauzi, Aditya
• Format: Article PeerReviewed
• Language: English; Indonesian; English; English
• Published: Elsevier
• Subjects: R5-920 Medicine (General)
• Online Access: https://repository.unair.ac.id/124800/1/9.%20artikel.pdf; https://repository.unair.ac.id/124800/2/9.%20karil.pdf; https://repository.unair.ac.id/124800/3/9.Korespondensi.pdf; https://repository.unair.ac.id/124800/4/9.turnitin.pdf; https://repository.unair.ac.id/124800/; https://www.sciencedirect.com/science/article/pii/S2049080120301540; https://doi.org/10.1016/j.amsu.2020.06.015
• Institution: Universitas Airlangga

Abstract Infantile hemangioma (IH) with concurrent cleft lip and palate is a rare case. Surgical management is often considered as the best management for infantile hemangioma with concurrent cleft lip and palate. However, considering the functionality aspect and aesthetic appearance, a plastic surgeon can also consider non-surgical management without interrupting the surgical timeline for the cleft lip and palate. This case report aimed to describe the role of oral propranolol and oral methylprednisolone for infantile hemangioma with concurrent cleft lip and palate alongside the surgical management for cleft lip and palate. A 2-month-old presented with complaints of swelling in her right upper nose and cheek along with cleft lip and palate. She was treated with oral propranolol and oral methylprednisolone. Labioplasty was performed when she was three months old. Palatoplasty and nasorraphy were done when she was one year old. A significant reduction of the hemangioma was seen and the corrective procedures showed a good result. The use of propranolol and methylprednisolone for infantile hemangioma in our patient shows a good result even when combined with labioplasty, palatoplasty, and nasorraphy for cleft lip and palate. The management of infantile hemangioma with concurrent cleft lip and palate using oral propranolol and oral methylprednisolone shows a good result with no side effects and can be elaborated with labioplasty, palatoplasty, and nasorraphy, and will not interrupt the cleft lip and palate surgical timeline.