Prolonged Maternal Separation Reduces Anxiety State and Increases Compulsive Burying Activity in the Offspring of BALB/c Mice

• Main Authors: Qais Jarrar, -, Rami Ayoub, -, Kawther Alhussine, -, Khang Wen Goh, -, Said Moshawih, -, Chrismawan Ardianto, -, Bey Hing Goh, -, Long Chiau Ming, -
• Format: Article PeerReviewed
• Language: English; English; English; English
• Published: Multidisciplinary Digital Publishing Institute (MDPI) 2022
• Subjects: R Medicine; RS Pharmacy and materia medica; RS1-441 Pharmacy and materia medica; RS200-201 Pharmaceutical dosage forms
• Online Access: https://repository.unair.ac.id/125175/1/Artikel%20C-7.pdf; https://repository.unair.ac.id/125175/2/%28C-07%29%20Kualitas%20Karil.pdf; https://repository.unair.ac.id/125175/3/Similarity%20C-7.pdf; https://repository.unair.ac.id/125175/4/Korespondensi%20C-7.pdf; https://repository.unair.ac.id/125175/; https://www.mdpi.com/2075-4426/12/11/1921; https://doi.org/10.3390/jpm12111921
• Institution: Universitas Airlangga

Background: The elevated plus maze (EPM) and the marble burying (MB) tests are common behavioral tests used for behavioral phenotyping in mouse models for neurodevelopmental disorders. However, the behavioral effects of maternal separation (MS), a standard paradigm for early life stress in animals,...