Antifungal activity of eugenol and clove leaf essential oil (Syzygium aromaticum L.) against clinical isolates of candida species
ABSTRACT Candida species are causative microorganisms of oropharyngeal, vulvovaginal, and skin infections. Clove (Syzygium aromaticum L.) and eugenol oil have considerable antifungal activity against human pathogenic fungi, including Candida species. The anticandidal action of the studied oils is s...
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Ecuador, South America
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id-langga.1253122023-10-12T02:29:26Z https://repository.unair.ac.id/125312/ Antifungal activity of eugenol and clove leaf essential oil (Syzygium aromaticum L.) against clinical isolates of candida species Dwi Murtiastutik, Dwi Irmadita Citrashanty, Irmadita Pepy Dwi Endraswari, Pepy Retno Widyowati, Retno Evy Ervianti, Evy Sawitri, Sawitri Rahmadewi, Rahmadewi Citra Dwi Harningtyas, Citra R5-920 Medicine (General) ABSTRACT Candida species are causative microorganisms of oropharyngeal, vulvovaginal, and skin infections. Clove (Syzygium aromaticum L.) and eugenol oil have considerable antifungal activity against human pathogenic fungi, including Candida species. The anticandidal action of the studied oils is significantly dependent on the concentration of eugenol and further main and minor constituents of the oils with well-known antifungal effects must have additional and synergistic activities. This study was conducted to compare the antifungal activity of clove leaf essential oil (Syzygium aromaticum L.) and eugenol to determine the role of the content other than eugenol in clove leaf essential oil as an antifungal against Candida species isolates from HIV-AIDS patients. Methods: This study is an in vitro test using the disk diffusion method to determine the zone of inhibition of clove leaf essential oil (Syzygium aromaticum L.) concentrations of 5%, 10%, and 15% as well as eugenol which was equivalent to the concentration of eugenol in clove leaf essential oil at concentrations of 5%, 10% and 15% in 40 isolates of Candida species. Ecuador, South America Article PeerReviewed text en https://repository.unair.ac.id/125312/1/11.%20Artikel_.pdf text id https://repository.unair.ac.id/125312/2/C-11%20Karil.pdf text en https://repository.unair.ac.id/125312/3/11.Korespondensi.pdf text en https://repository.unair.ac.id/125312/4/11.%20Tunitin.pdf text id https://repository.unair.ac.id/125312/9/11%20etik.pdf Dwi Murtiastutik, Dwi and Irmadita Citrashanty, Irmadita and Pepy Dwi Endraswari, Pepy and Retno Widyowati, Retno and Evy Ervianti, Evy and Sawitri, Sawitri and Rahmadewi, Rahmadewi and Citra Dwi Harningtyas, Citra Antifungal activity of eugenol and clove leaf essential oil (Syzygium aromaticum L.) against clinical isolates of candida species. International Journal of Health Sciences, 6 (S5). pp. 6768-6775. ISSN ISSN: 550-6978 E-ISSN 2550-696X https://sciencescholar.us/journal/index.php/ijhs/article/view/11530 10.53730/ijhs.v6ns5.11530 |
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R5-920 Medicine (General) Dwi Murtiastutik, Dwi Irmadita Citrashanty, Irmadita Pepy Dwi Endraswari, Pepy Retno Widyowati, Retno Evy Ervianti, Evy Sawitri, Sawitri Rahmadewi, Rahmadewi Citra Dwi Harningtyas, Citra Antifungal activity of eugenol and clove leaf essential oil (Syzygium aromaticum L.) against clinical isolates of candida species |
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ABSTRACT
Candida species are causative microorganisms of oropharyngeal, vulvovaginal, and skin infections. Clove (Syzygium aromaticum L.) and eugenol oil have considerable antifungal activity against human pathogenic fungi, including Candida species. The anticandidal action of the studied oils is significantly dependent on the concentration of eugenol and further main and minor constituents of the oils with well-known antifungal effects must have additional and synergistic activities. This study was conducted to compare the antifungal activity of clove leaf essential oil (Syzygium aromaticum L.) and eugenol to determine the role of the content other than eugenol in clove leaf essential oil as an antifungal against Candida species isolates from HIV-AIDS patients. Methods: This study is an in vitro test using the disk diffusion method to determine the zone of inhibition of clove leaf essential oil (Syzygium aromaticum L.) concentrations of 5%, 10%, and 15% as well as eugenol which was equivalent to the concentration of eugenol in clove leaf essential oil at concentrations of 5%, 10% and 15% in 40 isolates of Candida species. |
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Dwi Murtiastutik, Dwi Irmadita Citrashanty, Irmadita Pepy Dwi Endraswari, Pepy Retno Widyowati, Retno Evy Ervianti, Evy Sawitri, Sawitri Rahmadewi, Rahmadewi Citra Dwi Harningtyas, Citra |
author_facet |
Dwi Murtiastutik, Dwi Irmadita Citrashanty, Irmadita Pepy Dwi Endraswari, Pepy Retno Widyowati, Retno Evy Ervianti, Evy Sawitri, Sawitri Rahmadewi, Rahmadewi Citra Dwi Harningtyas, Citra |
author_sort |
Dwi Murtiastutik, Dwi |
title |
Antifungal activity of eugenol and clove leaf essential oil (Syzygium aromaticum L.) against clinical isolates of candida species |
title_short |
Antifungal activity of eugenol and clove leaf essential oil (Syzygium aromaticum L.) against clinical isolates of candida species |
title_full |
Antifungal activity of eugenol and clove leaf essential oil (Syzygium aromaticum L.) against clinical isolates of candida species |
title_fullStr |
Antifungal activity of eugenol and clove leaf essential oil (Syzygium aromaticum L.) against clinical isolates of candida species |
title_full_unstemmed |
Antifungal activity of eugenol and clove leaf essential oil (Syzygium aromaticum L.) against clinical isolates of candida species |
title_sort |
antifungal activity of eugenol and clove leaf essential oil (syzygium aromaticum l.) against clinical isolates of candida species |
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Ecuador, South America |
url |
https://repository.unair.ac.id/125312/1/11.%20Artikel_.pdf https://repository.unair.ac.id/125312/2/C-11%20Karil.pdf https://repository.unair.ac.id/125312/3/11.Korespondensi.pdf https://repository.unair.ac.id/125312/4/11.%20Tunitin.pdf https://repository.unair.ac.id/125312/9/11%20etik.pdf https://repository.unair.ac.id/125312/ https://sciencescholar.us/journal/index.php/ijhs/article/view/11530 |
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