Liver function characteristics of COVID-19 patients with obesity at Dr. Soetomo Hospital: case series
Background: Coronavirus disease 2019 (COVID-19) patients with obesity are more susceptible to liver injury. There is currently no published overview regarding COVID-19 patients with liver injury in Indonesia. Our study reported 7 cases of obese COVID-19 patients with an increase of serum glutamic ox...
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id-langga.1255852023-04-28T15:59:52Z https://repository.unair.ac.id/125585/ Liver function characteristics of COVID-19 patients with obesity at Dr. Soetomo Hospital: case series Erwin Maulana Farmanda Putra Ummi Maimunah RC31-1245 Internal medicine Background: Coronavirus disease 2019 (COVID-19) patients with obesity are more susceptible to liver injury. There is currently no published overview regarding COVID-19 patients with liver injury in Indonesia. Our study reported 7 cases of obese COVID-19 patients with an increase of serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT), followed by 5 of them developing severe symptoms of COVID-19 in isolation room of Dr. Soetomo Hospital Surabaya within June-December 2020. Case Presentation: A total of 7 COVID-19 patients, by the average age 46.2±15.5 years, were obese. The mean body mass index (BMI) was 36,3±3,4 kg/m2. Five of them experienced serious symptoms. There were 3 patients (patient no. 2, 4, 7) who had normal SGOT level, while the rest had an increased SGOT level for <2x upper limit of normal (ULN) at admission. During treatment, SGOT level increased in 5 patients for 1-<3x ULN and normal in the rest of them (patient no. 2, 4). Meanwhile, the normal SGPT levels were shown in 3 patients (patient no. 2, 4, 7) and increased in 4 others at admission for 1-<4x ULN. All of them tended to have an increased SGPT level during treatment for 1-<5x ULN. However, since the increase of SGOT and/or SGPT for >3x ULN is defined as liver injury, it happened in 2 patients that occur since admission (patient no. 3) and during treatment (patient no. 5). Conclusion: Obesity may impede the recovery of COVID-19 and manifest in the deterioration of liver function. Sanglah General Hospital 2022 Article PeerReviewed text en https://repository.unair.ac.id/125585/1/17.Liver_function_characteristics.pdf text en https://repository.unair.ac.id/125585/2/17.Karil_Liver_function_characteristics.pdf text en https://repository.unair.ac.id/125585/3/17.Similarity_Liver_function_characteristics.pdf image en https://repository.unair.ac.id/125585/4/17.Korespondensi.jpeg Erwin Maulana Farmanda Putra and Ummi Maimunah (2022) Liver function characteristics of COVID-19 patients with obesity at Dr. Soetomo Hospital: case series. Bali Medical Journal, 11 (3). ISSN 2302-2914 https://www.balimedicaljournal.org/index.php/bmj/article/view/3727/2360 |
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RC31-1245 Internal medicine Erwin Maulana Farmanda Putra Ummi Maimunah Liver function characteristics of COVID-19 patients with obesity at Dr. Soetomo Hospital: case series |
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Background: Coronavirus disease 2019 (COVID-19) patients with obesity are more susceptible to liver injury. There is currently no published overview regarding COVID-19 patients with liver injury in Indonesia. Our study reported 7 cases of obese COVID-19 patients with an increase of serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT), followed by 5 of them developing severe symptoms of COVID-19 in isolation room of Dr. Soetomo Hospital Surabaya within June-December 2020.
Case Presentation: A total of 7 COVID-19 patients, by the average age 46.2±15.5 years, were obese. The mean body mass index (BMI) was 36,3±3,4 kg/m2. Five of them experienced serious symptoms. There were 3 patients (patient no. 2, 4, 7) who had normal SGOT level, while the rest had an increased SGOT level for <2x upper limit of normal (ULN) at admission. During treatment, SGOT level increased in 5 patients for 1-<3x ULN and normal in the rest of them (patient no. 2, 4). Meanwhile, the normal SGPT levels were shown in 3 patients (patient no. 2, 4, 7) and increased in 4 others at admission for 1-<4x ULN. All of them tended to have an increased SGPT level during treatment for 1-<5x ULN. However, since the increase of SGOT and/or SGPT for >3x ULN is defined as liver injury, it happened in 2 patients that occur since admission (patient no. 3) and during treatment (patient no. 5).
Conclusion: Obesity may impede the recovery of COVID-19 and manifest in the deterioration of liver function. |
format |
Article PeerReviewed |
author |
Erwin Maulana Farmanda Putra Ummi Maimunah |
author_facet |
Erwin Maulana Farmanda Putra Ummi Maimunah |
author_sort |
Erwin Maulana Farmanda Putra |
title |
Liver function characteristics of COVID-19 patients with obesity at Dr. Soetomo Hospital:
case series |
title_short |
Liver function characteristics of COVID-19 patients with obesity at Dr. Soetomo Hospital:
case series |
title_full |
Liver function characteristics of COVID-19 patients with obesity at Dr. Soetomo Hospital:
case series |
title_fullStr |
Liver function characteristics of COVID-19 patients with obesity at Dr. Soetomo Hospital:
case series |
title_full_unstemmed |
Liver function characteristics of COVID-19 patients with obesity at Dr. Soetomo Hospital:
case series |
title_sort |
liver function characteristics of covid-19 patients with obesity at dr. soetomo hospital:
case series |
publisher |
Sanglah General Hospital |
publishDate |
2022 |
url |
https://repository.unair.ac.id/125585/1/17.Liver_function_characteristics.pdf https://repository.unair.ac.id/125585/2/17.Karil_Liver_function_characteristics.pdf https://repository.unair.ac.id/125585/3/17.Similarity_Liver_function_characteristics.pdf https://repository.unair.ac.id/125585/4/17.Korespondensi.jpeg https://repository.unair.ac.id/125585/ https://www.balimedicaljournal.org/index.php/bmj/article/view/3727/2360 |
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